Objectives The aim of this study was to compare the effects of hyaluronic acid (HA), N-acetyl cysteine (NAC), and deproteinized calf serum on cartilage healing after the creation of traumatic cartilage injury in a rat model. Materials and methods A total of 48 rats, each weighing an average of 350 g, were randomly separated into four groups of 12. An osteochondral defect was created, 2-mm-wide and 3-mm deep in each rat. Injections were made to the knees of the rats as saline solution in Group 1, deproteinized calf serum in Group 2, NAC in Group 3, and HA in Group 4. At the end of 12 weeks, all rats were sacrificed and tissues were evaluated histologically. Results The HA group had a better cell morphology, tissue morphology, surface architecture, and vascularity than the other groups (p<0.001). Matrix staining, chondrocyte clustering, and the assessment scores of the mid, deep, superficial zones, and overall were higher in the HA group than in the other groups (p<0.001). The NAC showed a better tissue morphology, cell morphology, and vascularity than the control group (p=0.003, p<0.001, and p<0.001, respectively). Conclusion Hyaluronic acid was the most effective agent in cartilage healing compared to NAC and deproteinized calf serum. In addition, the NAC was more effective compared to the control group.
Aim: The use of social media, especially Instagram, has become widespread in the medical field. The aim of this study was to evaluate Achilles tendon surgery from patients' perspectives by examining public posts on Instagram. Material and Methods: A retrospective analysis was made of the Instagram posts of patients with the hashtags #achillestendonsurgery and #achillestendonrepair between December 2018 and October 2021. In total, 234 posts (181 photographs, 53 videos) were evaluated and compared in terms of gender, sharing format (video, photo), sharing tone (negative, positive, neutral), content (activities of daily living, rehabilitation, cast/brace, hospital room, surgical site), country and popularity (the number of views for videos, the number of likes for photographs). Results: Posts in video format and a positive tone, posts on the rehabilitation process, and posts about male patients were found to have higher numbers of likes and views than other posts. The content of the shares were respectively; activity of daily living 36.8%(n=86), physical therapy 29.9%(n=70), cast/brace 20.1%(n=47), surgical site 7.7%(n=18), and hospital room 5.6%(n=13). The media tone of the posts was 40.2%(n=94) positive, 6.4%(n=15) negative, and 53.4%(n=125) neutral. Conclusions: Patients avoided making negative posts on their Instagram after Achilles tendon surgery, and often shared experiences of postoperative rehabilitation processes and daily living activities.
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