Background: Otitis media with effusion (OME) is the condition in which fluid was presented in the middle ear cavities with absence of signs or symptoms of acute infection. Most episodes of OME resolve within 3 months, without need for surgical intervention. The placement of tympanostomy tubes (TTs) is the treatment for persistent OME. Objective: This study is performed to compare between anterosuperior and anteroinferior insertion of tympanostomy tubes in treatment of otitis media with effusion. Methods: The study included 40 patients with bilateral OME (at least 3 months did not respond to medical treatment) , divided into two groups: Group (I) included 40 patients who had been undergone myringotomy and tympanostomy tubes insertion at antero-superior quadrant of one ear (Right ear). Group (II) included the same 40 patients who had been undergone myringotomy and tympanostomy tubes insertion at antero-inferior quadrant of other ear (left ear). All patients were exposed to complete history taking, ENT examination and audiological investigation (Tympanometry, Pure Tone Audiometry), follow up of cases by clinical and audiological investigations were performed at 1,2 and 6 months.
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