No abstract

SummaryAdenosarcoma is a rare tumour which usually originates from endometrium. This paper presents a 69-year-old woman with adenosarcoma of uterus and a history of breast cancer and 10 years tamoxifen therapy. BACKGROUND

No abstract

No abstract

Heavy snoring is associated with increased respiratory variation of the ballistocardiogram (BCG). The cause for this association is not known. Although the BCG is a sensitive method to measure myocardial performance, the validity of the signal as a marker of snoring-related haemodynamic changes has not been tested. The aim of this study was to investigate whether ballistocardiographic respiratory variation (BRV) correlates with intrathoracic pressure variation (IPV). The BRV and the IPV were measured in five healthy, normal-weight, awake adults during normal breathing, during breath-holding with constant intrathoracic pressure, and during breathing against increased respiratory resistance (high IPV). The BCG was recorded with the static charge-sensitive bed (SCSB) and the intrathoracic pressure with an oesophageal balloon. The mean BRV was significantly lower during central apnoea than during free breathing (8.2 versus 29.4% p less than 0.0001). When breathing against increased respiratory load, the BRV increased in a linear manner as function of the IPV (r = 0.68, p less than 0.01). There was significant interindividual variation in the response. We conclude that changes in the BRV reflect changes in the IPV. Further studies are needed to evaluate whether the BCG could be used as a noninvasive alternative to the oesophageal balloon in monitoring changes of respiratory resistance during heavy snoring.

Background:Salivary gland tumors of epithelial origin are rare lesions. Few epidemiologic studies on prevalence of such condition in Iranian population have been published. This study with the aim of determining the relative frequency of epithelial salivary tumors was performed in Yazd city from 2001 to 2012.Materials and Methods:Cases diagnosed as primary malignant epithelial salivary gland tumor were collected from the Pathology Department of main hospitals and Health Department of Medical Science Yazd University from 2001–2012. Histopathologic type, tumor location, age, gender and whether patients were native or non-native were analyzed.Results:Eighty-one cases of primary malignant epithelial salivary gland tumors were recorded. Male to female ratio was 1:1.3. The most common malignancy was adenoid cystic carcinoma (35.8%) and the most common effected site was the parotid gland. Mean age for malignancy was 52.57 ± 18.25 years.Conclusion:According to the findings of this study, predilection of adenoid cystic carcinoma was more in non-natives as compared to natives (from Yazd). This could suggest the influence of racial and environmental factors on prevalence of such malignancies.

Background: One of the most important factors in the fracture healing is the intracellular production of prostaglandins by osteoblast cells. Nonsteroidal anti-inflammatory drugs (NSAIDs) exert their effects through inhibition of prostaglandin synthesis. NSAIDs are widely used in orthopedic practices and their effect on bone healing is not fully understood yet. Objectives: The current study aimed at examining the effects of indomethacin and meloxicam on tibia fracture union in rats. Methods: The current study was conducted on 60 male rats. Mid-shaft tibia fracture was induced in rats using bone-breaker device. The animals were randomly divided into 3 groups; a control group that received distilled water and 2 other groups that received indomethacin and meloxicam respectively for 28 days. At the end of weeks 1, 2, 4, 8 and 12, four rats were randomly sacrificed from each group, and histological evaluation, measurement of the calcium, phosphorus, and alkaline phosphatase plasma levels, as well as radiographic examinations were performed on them. Results: After 4 weeks, a thin layer of woven bone was observed in the vast spaces of the bone marrow in the fracture area in the control group. In the meloxicam group in the week 4, the formation of immature blades of bone was observed, which were less organized and more irregular. In the indomethacin group in the week 4, new bone formation was less immature and more areas of cartilage were still observed. In the radiographic evaluations, delayed union in indomethacin and meloxicam groups was observed, which was more significant in the indomethacin group. Conclusions: Indomethacin and meloxicam had impact on the process of bone repair and delayed union in both groups of drugs. This delayed union was more significant in non-selective NSAIDs (COX-I and = II inhibitors) rather than selective NSAIDs (COX-II inhibitor).

Desmoids tumor is a rare neoplasm comprising about 0.03% of all neoplasms and less than 3% of all soft tissue tumors and is associated with high estrogen states. Classic manifestation of it is in the form of an abdominal lump distinct from uterus. Contributing to the formation of the tumor are the traumas arising from pregnancy including previous cesarean-induced scars. Our case, a 29-year-old woman with a medical history of cesarean section, had been reported with the pregnancy age of 8 weeks and 3 days and heterogenic hypoechoic tumor the size of 28×36mm with a rather distinct sidelines in the soft tissue at the left side of the scar with the possibility of endometriosis but the size amounted to 62×38mm at the time of elective cesarean section. Following cesarean and removal of the fetus, the tumor being separated from the uterus and located in the abdominal wall, was taken out that was then pathologically diagnosed as desmoids tumor.