BackgroundGliomas are the most prevalent intrinsic tumors of the central nervous system and are categorized from grade I to grade IV. Magnetic resonance imaging (MRI) provides exact diagnosis, prognosis, and assessment of tumor response to current chemotherapy/immunotherapy and radiation therapy. With histopathology serving as the gold standard, we aimed to assess the diagnostic accuracy of magnetic resonance spectroscopy (MRS) in predicting glioma grade.

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Background and aim: The evidence on isolated oligohydramnios (IO) patients and their postnatal outcomes are inconsistent. Recent research has clarified the connection between that IO and negative outcomes in the postnatal period. Our goal was to analyze the correlation between Doppler measurements and postnatal outcomes in oligohydramnios patients, with a focus on the cerebroplacental ratio (CPR).Methodology: A cohort study was conducted in the Radiology Department of Khan Research Laboratories (KRL) Hospital from October 2021 to July 2022. One hundred women were chosen as the sample size. For this study, we used the Raosoft sample size calculator with a 95% confidence interval and a 5% margin of error. Both the middle cerebral artery and the umbilical artery were imaged using ultrasound, and the systolic-todiastolic ratio and peak systolic velocity are recorded. Pulsatility index (PI) and resistive index (RI) were also calculated. If the amniotic fluid index (AFI) is less than 5 cm, the condition is known as oligohydramnios. The newborn's APGAR score was taken immediately after birth as well as after 5 minutes.Results: We have determined that, on average, mothers are 35.45 weeks/248.15 days pregnant. When compared to the reference standard, CPR diagnostic features showed a sensitivity of 92% and a specificity of 77.27. Overall diagnostic accuracy is predicted to be 93.0%, with a 93.50% positive prognosis and a 73.91% negative prognosis. The effect size for the change in APGAR scores before and after the test was -2.38 1.03, with a 95% confidence interval of -2.58 to -2.17 and a significance level of 0.00. Conclusion:This study concludes that CPR is an effective screening tool and that it can be used to predict postnatal outcomes in patients with oligohydramnios. Clinical prediction rules were found to be a more effective screening tool, with a sensitivity of 92%, a specificity of 77.27%, and a diagnostic accuracy of 92.3%.

Objective: To assess the diagnostic accuracy of magnetic resonance imaging (MRI) in detecting invasive placentas using per-operative findings as the gold standard.Methodology: A prospective cross-sectional study was conducted in the diagnostic radiology department of KRL General Hospital Islamabad during Oct 2019 to Sep 2021. Sixty prenatal individuals were identified as having a high risk of invasive placenta and underwent MRI (Phillips 1.5 T) to confirm the diagnosis. A trainee radiologist and a consultant radiologist reviewed the images. The MRI's sensitivity, specificity, positive predictive value, negative predictive value, and accuracy was calculated using a 2×2 contingency tables. Results: Ten cases of invasive placenta were detected postoperatively (gold standard). The MRI had a sensitivity of 90%, a specificity of 93%, a positive predictive value of 90%, a negative predictive value of 90%, and an accuracy of 92.3 percent, respectively. Conclusion: The study concluded that magnetic resonance imaging (MRI) offers a good diagnostic accuracy and is a reproducible technology for prenatal identification of invasive placentas.