Background: Women with Hypothyroidism have higher pregnancy complication rates. Objective: The purpose of the present study was to compare the effects of clinical and subclinical hypothyroidism on maternal outcomes. Methodology: This cohort study was conducted in the Feto-Maternal Department of Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh from a period of 6 months dated from September 2019 to February 2020 for a period of 6 months. All cases of the clinical and sub-clinical hypothyroid pregnant women admitted in this department. Maternal outcomes of both groups during pregnancy were recorded. Findings of the cases recorded carefully. Result: This study was conducted among 75 patients, which was 14.79% of the total admitted cases during study period. Maximum (62.79%) number was found in the age group of 25 to 44 years in group I and 65.62% cases in group II. (p<0.05). Severe Pre Eclampsia was observed 2(4.65%) cases and 6(18.75%) Group II. Abruptio placenta was observed 5(15.62%) cases in group II and none in group I. However Preterm delivery are three times more 39.5% in group I cases. Uterine rupture, abortion are observed only in group II patients (p<0.05). Conclusion: In conclusion maternal outcomes are significantly varied in clinical and subclinical hypothyroidism women during pregnancy. Journal of Current and Advance Medical Research, January 2021;8(1):7-11
Conclusions: This series confirms that hyperechogenic lung malformations reflect a heterogeneous group of lesions. Symptoms at birth are present in 9% and cannot be predicted by antenatal features nor by the underlying cause. VP10.11 Aorta-porto-umbilical vein shunt in association with pulmonary sequestration
Objectives: To assess outcome of children diagnosed prenatally with microcephaly (head circumference smaller than 2 standard deviations below the mean) at Fetal Medicine of Policlinico Sant'Orsola, Bologna. Methods: A retrospective cohort study of singleton pregnancies, suspected for microcephaly and examined by multiplanar fetal neurosonogram, according to ISUOG guidelines, between January 2008 and March 2020. Results: Over 12 years, 48 singleton microcephalic fetuses, were found in our archives. 12 underwent voluntary termination because this finding (isolated or associated with other abnormalities). Diagnosis was performed during late second trimester and confirmed as isolated for 22 fetuses (46%). In four cases a concomitant heart disease was found. The mean gestational age at delivery was 36.5 weeks. A head circumference below the 5th centile was confirmed for 8 newborns (36%). Complete results are collected in table 1. Conclusions: All the confirmed microcephalic newborns had normal chromosomes, no other structural abnormalities and no evidence of intrauterine infection or maternal alcohol/drug abuse. The pediatric followup was, at time of this study, available only for 7 newborns and documented a normal neurologic development per age. The postnatal ultrasound examination do not prove the presence of other abnormalities. All these findings should help in the counselling of couples referred for a prenatal isolated microcephaly.
Background: Prediction of pre-eclampsia is very important during pregnancy. Objective: The purpose of the present study was to find out the role of maternal serum placental protein 13 at 11 to 13 weeks of pregnancy as a predictor of pre-eclampsia. Methodology: This prospective cohort study was carried out including 83 pregnant women with early gestation (11-13 weeks) attending the antenatal clinic of BSMMU hospital, Dhaka, during the period of July 2019 to December 2019 for a period of six months. Maternal serum was taken for measurement of Placental Protein 13 by ELISA technique. Then the subjects were regularly followed up to term. At each visit they were clinically evaluated by measuring blood pressure and testing urine for protein by heat coagulation method. Proteinuria was confirmed by measuring 24 hour urinary total protein. Result: Out of 83 cases, 5 developed preeclampsia. The mean value of Placental Protein 13 in non-preeclampsia patients was 167.5±8.79 and in pre-eclamptic patients was 131.54±20.06. The cutoff point value of Placental Protein 13 for prediction of preeclampsia was 0.68 MoM. Area under curve (AUC) was 0.93. Sensitivity, specificity, positive predictive value and negative predictive value of this test were 80.00%, 94.94%, 50.00% and 98.68% respectively. The accuracy of this test was 93.98%. Conclusion: In conclusion maternal serum Placental Protein 13 can predict risk of development of preeclampsia. Journal of National Institute of Neurosciences Bangladesh, January 2021, Vol. 7, No. 1, pp. 47-51
Background: Stones in the urinary tract is a common medical problem in the general population. At present, the great expansion in minimally invasive techniques has led to the decrease in open surgery. Extracorporeal shock wave lithotripsy (ESWL) has been introduced as an alternative approach which disintegrates stones in the kidney and upper urinary tract through the use of shock waves. Nevertheless, as there are limitations with the success rate in ESWL, other minimally invasive modalities for kidney stones such as percutaneous nephrolithotomy (PCNL) is also widely applied. There is a trend of using ESWL for treatment of renal stones smaller than 1 cm and PCNL in those with stones greater than 2 cm. Nevertheless, no consensus regarding treatment of renal stones between 1 to 2 cm stones. The objective of this prospective study was to compare the results of ESWL and PCNL for treatment of 1 to 2 cm renal stones. Method : This is a quasi experimental study. This study was conducted to compare the efficacy and safety of percutaneous nephrolithotomy (PCNL) and extracorporeal shock wave lithotripsy (ESWL) in treating 10 to 20 mm sized renal stone among the Bangladeshi population. This prospective study conducted between the periods of September, 2011 to August, 2012 in the department of urology, Bangabandhu Sheikh Mujib medical university (BSMMU) Hospital. All the patients attending the urology outpatient clinic with 10 to 20mm renal calculi were the study population. A total of 70 subjects were enrolled for this study and they were equally divided into two groups so that each group had 35 subjects. The one group received PCNL whereas the other group received ESWL. Statistical analyses of the results were obtained by using window based computer software devised with Statistical Packages for Social Sciences (SPSS-15). Results: There is no statistically significant difference in regarding age, sex, stone side(lt. or rt.), the distribution of stone (upper, middle and lower calyx) and size between the groups (p>0.05). At 3 month follow up among the patients in ESWL group stone cleared and not cleared were 25(71.4%) and 10(28.6%) respectively and at 3 month follow up among the patients in PCNL group stone cleared and not cleared were 33(94.3%) and 2(5.7%)respectively. There is statistically significant difference in stone clearance rate at 3 month follow up between the groups (p<0.05). All patients in ESWL group developed post procedure haematuria 35(100.0%). Other post procedure complications among the ESWL group pain, fever and steinstrasse were 12(34.3%), 07(20.0%) and 03(08.6%) respectively. Common post procedure complications among the patients of PCNL group pain, haematuria and fever were 11(31.4%), 33(94.3%) and 13(37.1%) respectively. Other post procedure complications in PCNL group were vomiting (8.6%), urinary leakage (5.7%), wound infection (11.4%) and urinary cutaneous fistula (5.7%). There was no statistically significant difference post procedure pain, haematuria and fever between the groups (p>0.05), but statistically significant difference observed in steinstrasse and wound infection between the groups (p<0.05). Mean±SD of hospital stay among the patients of ESWL group and PCNL group was 1.37±0.65 and 4.34±1.43 days respectively. There is statistically significant difference in hospital stay between the groups (p<0.05). Conclusion: Though some specific complications which can be treated conservatively are more in PCNL group it may be concluded that the treatment with PCNL is better option than ESWL among the patients having renal calculi 10 to 20 mm. Bangladesh Journal of Urology, Vol. 21, No. 2, July 2018 p.98-104
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