Polyglandular polyendocrine syndromes (PSs) are an assorted collection of infrequent ailments considered by autoimmune motion contrary to more than one endocrine organ, though non-endocrine organs can be affected. The deficiency of parathyroid is quite rare without surgery. This article summarises clinical, epidemiological, and serological, data of patients with PSs. Multifaceted diagnostic difficulties and treatment choices required that the patient be admitted to the hospital for a rather long period, namely for six weeks. Three diabetic patients with various thyroid disorders such as lymphocytic thyroiditis involving parathyroid glands manifesting with severe hypothyroid and hypo-parathyroid status were studied with an occurrence of dengue viral aetiology as a precipitating factor. Further, the patients were investigated for the determination of antibodies against thyroglobulin and microsomal antigens by chemiluminescent microparticle immunoassay. They were also tested for Parathyroid Hormone and 25-hydroxy vitamin D. After three months, all the three hormonal status were brought to normal with substitution and maintenance therapy, and patients were reviewed after six months were found to maintain with the dose. To conclude, thyroiditis may progress during the progression of dengue fever and should be counted as a manifestation of expanded dengue syndrome.
Background: Breast cancer is the most common female cancer worldwide representing nearly 25% of the population. The study was designed to find the correlation between mammographic screening and histopathology in the diagnosis of malignancy among patients breast disease.Methods: This analytical study was done on 163 patients who came to the General Surgery Out-Patient Department, VMMC, Karaikal were screened. From this, 125 patients who were clinically diagnosed with benign breast disease were further evaluated with mammography. A detailed history, clinical examination, and investigations including mammography, histopathological examination in the operated specimen were done.Results: In the study 10% lump in the central area, 20% in lower inner quadrant, 12% in lower outer quadrant, 22% in upper inner quadrant and 36% in upper outer quadrant. In the study, all the 100 subjects were diagnosed to have a benign lesion in mammogram, in hpe 87% were diagnosed to have benign lesion and 13% were diagnosed to have malignant lesions.Conclusions: Even though BI-RADS 2 and 3 mammography showed the majority of benign lesions, there is an increasing trend of malignancy in higher BI-RADS criteria, on further histopathological examination. Sensitivity, positive predictive value, and diagnostic accuracy are very high for mammographic screening.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.