Despite great advances in medicine, the proper treatment of arterial hypertension (AH), diabetes mellitus (DM) and chronic kidney disease (CKD) remains a major challenge. Untreated, undiagnosed AH or DM may lead to the development of CKD and consequently to the occurrence of cardiovascular events. Adropin and irisin are newly discovered proteins which may play a role in the development and progression of the chronic diseases mentioned above. Endothelium dysfunction could be a bonding point. The following review paper focuses on adropin and irisin concentrations and their correlations in AH, DM and CKD. Lower adropin concentrations have been measured in patients with primary AH when compared to healthy volunteers. Irisin has reduced blood pressure on nitric oxide (NO)-dependent pathways in experimental studies; a negative correlation between irisin and blood pressure values has also been observed in preeclamptic women. Irisin also plays a role in insulin sensitivity and metabolic disorders. Lower irisin levels have been observed in patients with DM type 2 in comparison to a nondiabetic control group. It is also lower in the serum of pregnant women with gestational DM. A negative correlation between irisin and estimated glomerular filtration rate (EGFR) has also been noted. Adropin and irisin are newly described myokines measured in human plasma in healthy and disease status. Their exact function has not been specified yet and requires further studies.
Purpose: To evaluate diet, frequency and type of products consumed and offered at school shops. Materials and methods: Studies were conducted in 2014 among 159 pupils of three randomly selected schools in Bialystok (elementary school, middle school, and high school). The original anonymous questionnaire was used as a research tool. Analysis of results depending on age of the respondents was performed using contingency tables and Pearson's chi-squared test. For hypothesis testing evaluation, significance level of 0.05 was assumed. Results: Consumption of four or more meals during the day was declared by more than half of respondents. Three meals were consumed by 41.5% of middle school pupils, 29.8% of primary school children, and 27.1% of secondary school pupils. Percentage of pupils eating meals outside the home increased with age. Elementary school pupils (91.5%) took water to school significantly more often than middle school or high school pupils (64.2% and 54.2% respectively) (p<0.05). The highest percentage of pupils buying fast food at school was elementary school children, while sweet rolls were mostly bought by middle school pupils (75.5%). Elementary school pupils (78%) are provided information on healthy eating habits from family and school, while middle school (66%) and high school pupils (74.6%) receive this information from the media and magazines. Conclusions: Dietary mistakes reported in the group of pupils were more pronounced with age of respondents. Buying at school shops was associated with an increase in the amount of junk food at the cost of nutritious food
Introduction: Whipple’s disease is a chronic systemic infectious disorder with Tropheryma whipplei as an etiologic agent, occurring rarely and affecting numerous organs and systems. The variety of symptoms and a non-typical course make it difficult to establish a proper diagnosis. Purpose: In this study, etiopathogenesis, diagnostics and treatment of Whipple’s disease were presented based on the case report of 60-year-old man diagnosed with Whipple’s disease. Case presentation: Persistent diarrhoea with weight loss, lymphadenopathy in the abdominal cavity and moderate microcytic anemia predominated in the clinical picture. Diagnosis was put based on the clinical picture and macroscopic assessment of the small intestine and the presence of macrophages filled with a PAS-positive substance in the lamina propria. To deepen diagnostics, samples collected were assessed showing macrophages with the damaged mucosa, containing numerous elongated micro-organisms whose ultrastructure corresponded to Tropheryma whipplei. The patient’s clinical conditions improved after antibiotic therapy. Conclusions: It is vital to remember about Whipple’s disease in patients with chronic diseases due to a non-specific clinical picture and difficulties in establishing a proper diagnosis. When the disease is diagnosed unequivocally, proper and effective antibiotic therapy should be instituted immediately.
________________________________________________________________________________________________________________ Introduction:One of the major nutritional mistakes committed by children and adolescents is snacking between meals. Sweet or salty snacks are rich in simple sugars, fats, preservatives and dyes, and poor in minerals and vitamins. Their excessive consumption can lead to the development of dietrelated diseases in the future. Purpose: To evaluate the nutrition of children and adolescents with a focus on snacking between meals. Materials and methods:The study included 162 students from Bialystok schools, of which primary school students accounted for 30.2%, junior high school 38.3%, high school 31.5%. The questionnaire used by the authors contained 27 questions. Results: Regular meals were consumed by only 55.1% of primary school students, 35.5% of junior high school, and 37.3% of high school students. Two and fewer meals a day were consumed by 1.6% to 5.8% of the students studied. First breakfast was omitted by 18.4% of the students in elementary school, 16.1% of junior high school, and 15.7% of high school. Second breakfast was omitted by 12.9% to 17.6% of the respondents.
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