The chemical composition and biological activity of a sample of yellow propolis from Mato Grosso do Sul, Brazil (EEP-Y MS), were investigated for the first time and compared with green, brown, and red types of Brazilian propolis and with a sample of yellow propolis from Cuba. Overall, EEP-Y MS had different qualitative chemical profiles, as well as different cytotoxic and antimicrobial activities when compared to the other types of propolis assessed in this study and it is a different chemotype of Brazilian propolis. Absence of phenolic compounds and the presence of mixtures of aliphatic compounds in yellow propolis were determined by analysing 1H-NMR spectra and fifteen terpenes were identified by GC-MS. EEP-Y MS showed cytotoxic activity against human tumour strain OVCAR-8 but was not active against Gram-negative or Gram-positive bacteria. Our results confirm the difficulty of establishing a uniform quality standard for propolis from diverse geographical origins. The most appropriate pharmacological applications of yellow types of propolis must be further investigated.
espécie existe principalmente nos Estados do Acre, Amazonas, Amapá, Roraima e Pará. Na medicina popular, Stryphnodendron adstringens (Mart.) é uma planta utilizada no tratamento de algumas patologias como: gonorreia, leucorreia, diarreia, úlceras, hemorragias vaginais, impinges, assim como, pode ser usada como agente anti-inflamatório, cicatrizante, adstringente, hemostático, antisséptico e anti-hipertensivo. O barbatimão possui vários compostos produzidos pelo seu metabolismo secundário, como: os alcaloides, terpenos, flavonoides, esteroides e taninos. A atividade farmacológica dessa planta é devido principalmente ao teor de taninos presentes na espécie. Dessa forma, esta revisão aborda uma breve descrição botânica, taxonomia e distribuição geográfica, assim como os aspectos etnobotânicos, fitoquímicos e farmacológicos da espécie.
AbstractStryphnodendron adstringens (Mart.) is widely distributed in five Brazilian regions, popularly known as
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