High-dose cyclophosphamide and high-dose carboplatin are effective in the initial treatment of neuroblastoma; combined with surgery they produce some response in most patients. Nevertheless, the CR/VGPR rate reaches only 53%. Survival time has also been prolonged but most patients relapse with metastases.

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Papillary fibroelastoma of the aortic valve is an uncommon benign tumor of the heart that can present with embolic events. We report a case of 54-year-old lady with exertional chest pain and prior history of ST segment elevation myocardial infarction who was subsequently found to have a fibroelastoma of the aortic valve. The absence of angiographically significant coronary artery disease and resolution of anginal symptoms post-surgery in our patient points to the possibility of fibroelastoma causing these anginal symptoms. Although uncommon, fibroelastoma are being recognized more frequently with the help of transesophageal echocardiography. Hence, in the absence of significant coronary artery disease, we emphasize the importance of consideration of papillary fibroelastoma of the aortic valve as a cause of angina. We also discuss the key aspects of the fibroelastoma including presentation, diagnostic modalities and treatment options. Core tip: Papillary fibroelastoma of the aortic valve is an uncommon benign tumor of the heart which can present with embolic events. In this report we present a 54-year-old female with prior history of ST segment elevation myocardial infarction who presented with exertional chest pain. She was subsequently found to have a papillary fibroelastoma of the aortic valve.Aryal MR, Badal M, Mainali NR, Jalota L, Pradhan R. Papillary fibroelastoma of the aortic valve: An unusual cause of angina.

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