Background: The increased prevalence of obesity among children determined the rising number of its comorbidities in children and adults, too. This study aimed to evaluate certain markers of inflammation and insulin resistance in obese pediatric patients, identifying those who are more likely to develop further complications. Methods: We included 115 obese pediatric patients: 85 overweight and obese patients in the study group and 30 normal-weight patients in the control group. We calculated the body mass index (BMI) and we evaluated markers (biological, inflammatory) and the hormones profile. Results: Low-threshold inflammation was assessed by measuring interleukin 6 IL-6 and Intercellular Adhesion Molecules (ICAM). The analysis showed that IL-6 is significantly correlated with glucose (p = 0.001) and BMI value (p = 0.031). ICAM correlates significantly with triglycerides (p = 0.001), glucose (p = 0.044) and BMI percentile (p = 0.037). For pediatric obese patients, endotoxemia has been significantly correlated only with BMI percentile (p = 0.001). Plasma cortisol did not show significant correlations with total cholesterol, triglycerides, glucose or BMI percentile. The results indicated a significant predictive power of BMI percentile on inflammatory markers: IL-6 (AUC = 0.803, p < 0.001), ICAM (AUC = 0.806, p < 0.001) and endotoxemia (AUC = 0.762, p = 0.019). Additionally, BMI percentile has a significant predictive power for metabolic markers of insulin resistance (insulin value: AUC = 0.72, p < 0.001 and HOMA index: AUC = 0.68, p = 0.003). Conclusions: The study highlighted the importance of early markers of cardiovascular risk in obese pediatric patients represented by IL-6, ICAM, endotoxemia and their correlation with metabolic markers of insulin resistance represented by insulinemia, HOMA index and plasma cortisol. It can clearly be considered that the BMI percentile has significant predictive power for metabolic markers of insulin resistance.
Over time, it has been proven that practical demonstrations are very useful for understanding the course-based teaching style. Thermography can be very useful as a research tool by students to accurately measure the temperature differences of the various elements studied. The objective of this paper is to present the thermography as a useful technique for supporting the teaching process at the Medical Biotechnology classes at the Faculty of Medical Bioengineering, UMF Ia?i. The aim is to help students learn and understand the phenomena involved in heat transfer modes in a quick and intuitive way using the thermographic camera. The set of practical exercises presented in this paper was designed to allow students to observe the thermal effects of chemical reactions that are accompanied by temperature changes, either exothermic or endothermic reactions, which makes clear to understand thermochemistry which is the subject study of thermal effects associated with chemical reactions, applying the principle of thermodynamics. Thermography allows us to revolutionize this approach by facilitating the implementation of simple experiments. Infra-Red Thermography has become popular in different fields, such as engineering, textile industry, sports, and medical sciences. Moreover, it allows the determination of surface temperature, including skin temperature.A thermal imaging camera can be a very useful tool in the hands of today's science educator. Incorporating thermal imaging into science lectures and laboratory sessions greatly enhances the classroom experience by providing visual evidence of a scientific phenomenon.Classical methods typically limit the observation space around the demonstrator and can lead to students 'turning off' if not sufficiently
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