Objective To correlate the immunohistochemically of decreased E-cadherin expression for the long-term or recurrence-free survival of patients, using a threshold detected loss of E-cadherin expression with patient age, clinical and biological variables, and to investigate value of 40% for the relative amount of positively stained tumour cells, or for any other threshold value the prognostic value of these variables for the relapsefree and overall survival of patients with diCerent calculated (25%, 60% or 75%). However, comparing a follow-up of 16 months in patients with <40% stages of newly diagnosed prostate cancer. Patients and methods Sixty-seven patients (median age positivity and 46 months in patients with Á40% positivity, those patients retaining E-cadherin 63 years, range 48-78) undergoing radical prostatectomy for the treatment of primary prostate cancer expression had a significantly longer recurrence-free interval after radical prostatectomy (P<0.01). were assessed to determine whether age, tumour stage, histological grading, serum levels of prostate specific Conclusion The value of E-cadherin expression as an additional independent prognostic variable for patients antigen and prostatic acid phosphatase, regional lymph node status and E-cadherin expression were with primary prostate cancer is questionable. Keywords E-cadherin, expression, prostate cancer, radprognostic factors for relapse-free and overall survival. Results With a median (range) follow-up of 54 (3-193) ical prostatectomy, clinical prognosis months, there was no independent prognostic value brane 120 kDa glycoprotein belonging to the group of

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Objectives To evaluate the long-term continence rate, frequency of complications other than urinary retention was significant during and after surgery, at 27%, including subjective satisfaction and therapyassociated morbidity, of patients undergoing Stamey and in accord with the complication rate reported in earlier studies. bladder neck suspension. Patients and methods Eighty-five women (median ageConclusions Compared with other bladder neck suspension procedures, e.g. Burch colposuspension, the 55 years, range 30-85) with urinary stress incontinence treated by Stamey bladder neck suspension at Stamey procedure appears to be associated with a higher frequency of postoperative recurrent urinary our institution between 1987 and 1995 were evaluated using an anonymous questionnaire over a mean stress incontinence. Therefore, the Stamey procedure should only be used if the patient demands a minimally (range) follow-up of 61 (13-93) months. Results Of the 85 patients, 44 (52%) reported an invasive surgical procedure for bladder neck suspension. Although #60% of patients were satisfied with improvement in clinical symptoms at the evaluation and 29 (34%) were completely continent after the the durable improvement in clinical symptoms, it is appropriate to inform patients before surgery of the Stamey procedure. However, 53 (62%) patients reported subjective satisfaction with the result, because high recurrence rate after Stamey bladder neck suspension. they had a durable improvement in continence for a mean (range) of 44 (10-79) months. There was noKeywords Stamey bladder neck suspension, questionnaire-based analysis, long-term continence, compli-correlation between the number of previous urogynaecological operations undergone by the patients and cations, subjective satisfaction the success of the Stamey procedure. However, the like colporrhaphy or pubococcygeal plasty are associated