Subgraph matching algorithms are used to find and enumerate specific interconnection structures in networks. By enumerating these specific structures/subgraphs, the fundamental properties of the network can be derived. More specifically in biological networks, subgraph matching algorithms are used to discover network motifs, specific patterns occurring more often than expected by chance. Finding these network motifs yields information on the underlying biological relations modelled by the network. In this work, we present the Index-based Subgraph Matching Algorithm with General Symmetries (ISMAGS), an improved version of the Index-based Subgraph Matching Algorithm (ISMA). ISMA quickly finds all instances of a predefined motif in a network by intelligently exploring the search space and taking into account easily identifiable symmetric structures. However, more complex symmetries (possibly involving switching multiple nodes) are not taken into account, resulting in superfluous output. ISMAGS overcomes this problem by using a customised symmetry analysis phase to detect all symmetric structures in the network motif subgraphs. These structures are then converted to symmetry-breaking constraints used to prune the search space and speed up calculations. The performance of the algorithm was tested on several types of networks (biological, social and computer networks) for various subgraphs with a varying degree of symmetry. For subgraphs with complex (multi-node) symmetric structures, high speed-up factors are obtained as the search space is pruned by the symmetry-breaking constraints. For subgraphs with no or simple symmetric structures, ISMAGS still reduces computation times by optimising set operations. Moreover, the calculated list of subgraph instances is minimal as it contains no instances that differ by only a subgraph symmetry. An implementation of the algorithm is freely available at https://github.com/mhoubraken/ISMAGS.

Supplementary data are available at Bioinformatics online.

Traditional traffic monitoring systems are mostly based on road side equipment measuring traffic conditions throughout the day. With more and more GPS enabled connected devices, Floating Car Data (FCD) has become an interesting source of traffic information, requiring only a fraction of the road side equipment infrastructure investment. While FCD is commonly used to derive historic travel times on individual roads and to evaluate other traffic data and algorithms, it could also be used in traffic management systems directly. However, as live systems only capture a small percentage of all traffic, its use in live operating systems needs to be examined. In this paper, we investigate the potential of FCD to be used as input data for live automated traffic management systems. The FCD in this study is collected by a live country-wide FCD system in the Netherlands covering 6-8% of all vehicles. The (anonymised) data is first compared to available road side measurements to show the current quality of FCD. It is then used in a dynamic speed management system and compared to the installed system on the studied highway. Results indicate the FCD setup can approximate the installed system, showing the feasibility of a live system.

Physarum polycephalum, a true slime mold, is a primitive, unicellular organism that creates networks to transport nutrients while foraging. The design of these natural networks proved to be advanced, e.g. the slime mold was able to find the shortest path through a maze. The underlying principles of this design have been mathematically modeled in literature. As in real life the slime mold can design fault tolerant networks, its principles can be applied to the design of man-made networks. In this paper, an existing model and algorithm are adapted and extended with stimulation and migration mechanisms which encourage formation of alternative paths, optimize edge positioning and allow for automated design. The extended model can then be used to better design fault tolerant networks. The extended algorithm is applied to several national and international network configurations. Results show that the extensions allow the model to capture the fault tolerance requirements more accurately. The resulting extended algorithm overcomes weaknesses in geometric graph design and can be used to design fault tolerant networks such as telecommunication networks with varying fault tolerance requirements.Keywords bio-inspired algorithm · fault tolerant network design · mathematical modeling · network optimization · Physarum polycephalum

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Abstract-Applying the current technological possibilities has led to a wide range of traffic monitoring systems. These heterogeneous data sources individually provide a view on the current traffic state, each source having its own properties and (dis)advantages. However, these different sources can be aggregated to create a single traffic state estimation. This paper presents a data fusion algorithm that combines data on the data sample level. The proposed system fuses floating car data with stationary detector data and was implemented on live traffic. Results show the fusion algorithm allows to eliminate individual source bias and alleviates source-specific limitations.

The aim of this paper is to demonstrate the feasibility of a live Automated Incident Detection (AID) system using only Floating Car Data (FCD) in one of the first large-scale FCD AID field trials. AID systems detect traffic events and alert upcoming drivers to improve traffic safety without human monitoring. These automated systems traditionally rely on traffic monitoring sensors embedded in the road. FCD allows for finer spatial granularity of traffic monitoring. However, low penetration rates of FCD probe vehicles and the data latency have historically hindered FCD AID deployment. We use a live country-wide FCD system monitoring an estimated 5.93% of all vehicles. An FCD AID system is presented and compared to the installed AID system (using loop sensor data) on 2 different highways in Netherlands. Our results show the FCD AID can adequately monitor changing traffic conditions and follow the AID benchmark. The presented FCD AID is integrated with the road operator systems as part of an innovation project, making this, to the best of our knowledge, the first full chain technical feasibility trial of an FCD-only AID system. Additionally, FCD allows for AID on roads without installed sensors, allowing road safety improvements at low cost.