Current restorative materials with high fluoride release generally have lower mechanical properties. Therefore they may not be as durable clinically as lower fluoride release materials, particularly in load bearing areas. The aim of the present study is to explore the fluoride release and recharging ability as well as its compressive strength of the newly developed material called Giomer. The name Giomer is a hybrid of the words Glass Ionomer and Composite. Giomer contain a revolutionary PRG (Pre Reacted Glass) filler technology. They have properties of both conventional Glass Ionomer (fluoride release and recharge) and resin Composite (excellent esthetics, easy polishability and biocompatibility). MATERIALS & METHODS: Seven disk specimens of Giomer, Compomer and Glass Ionomer restorative materials were prepared for measurement of fluoride release and recharge using Ion Chromatography (IC) anion analyzer machine. Another seven disk specimens of Giomer, Compomer and Composite restorative materials were prepared for measurement of compressive strength using Universal Testing Machine (UTM). RESULTS: The value of compressive strength of Giomer is greater than that of Composite and Compomer but the fluoride release capability of Giomer becomes low in comparison to Glass Ionomer but not significant in comparison to compomer. CONCLUSIONS: Giomer have high compressive strength (271 Mpa) and an initial fluoride (1.41 ppm) release. It also exhibit fluoride recharge capabilities. So, Giomer to be a better restorative material other than any fluoride releasing materials. DOI: http://dx.doi.org/10.3329/updcj.v2i2.15533 Update Dent. Coll. j: 2012; 2 (2): 28-37
Vitex peduncularis (Verbenaceae), a perennial tree, is locally utilized for possessing multifaceted pharmacological properties including analgesic, antimalarial, anti-angina, antidiabetic, antioxidant, anti-inflammatory and hepatoprotective. Hence, this study aims to evaluate their antioxidant, thrombolytic, cytotoxic and antibacterial activities from the methanolic crude extract and its various solvent fractions. Data from antioxidant and thrombolytic assay displayed that Kupchan partitioned chloroform soluble fraction revealed the maximum phenolic content (73.39 mg of GAE/g of extract), DPPH free radical scavenging activity (26.69 μg/ml) and thrombolytic activity (37.35%). In brine shrimp lethality evaluation, the LC50 values indicate that the most cytotoxic compound was found to be from ethyl acetate soluble fraction (LC50 6.73 μg/ml). Finally, antibacterial activity of different fractions showed that both chloroform and methanolic fraction possessed mild activity against the tested bacteria. The potential biological effects of the crude fractions have been demonstrated demanding future studies of the isolated compounds to assess these activities. Bangladesh J. Sci. Ind. Res. 57(4), 239-246, 2022
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