The diagnosis of tuberculosis (TB) in osteoarcheological series relies on the identification of osseous lesions caused by the disease. The study of identified skeletal collections provides the opportunity to investigate the distribution of skeletal lesions in relation to this disease. The aim of this study was to examine the skeletal evidence for TB in late adolescent and adult individuals from the identified human collection of the Certosa cemetery of Bologna (Italy, 19th-20th c.). The sample group consists of 244 individuals (138 males, 106 females) ranging from 17 to 88 years of age. The sample was divided into three groups on the basis of the recorded cause of death: TB (N = 64), pulmonary non-TB (N = 29), and other diseases (N = 151). Skeletal lesions reported to be related to TB were analyzed. The vertebral lesions were classified into three types: enlarged foramina (EnF, vascular foramina with diameter of 3-5 mm), erosions (ER), and other foramina (OtF, cavities of various shapes > 3 mm). A CT scan analysis was also performed on vertebral bodies. Some lesions were seldom present in our sample (e.g., tuberculous arthritis). OtF (23.7%) and subperiosteal new bone formation on ribs (54.2%) are significantly more frequent in the TB group with respect to the other groups. The CT scan analysis showed that the vertebrae of individuals who have died of TB may have internal cavities in the absence of external lesions. These traits represent useful elements in the paleopathological diagnosis of TB.

The purpose of this paper is to present the identified skeletal collection (by age, sex, cause of death, occupation and preservation state) from the Certosa Cemetery of Bologna (Italy), which was reviewed and checked through a consultation of the cemetery archives. The collection consists of 425 skeletons of individuals (from newborn to 91 years old) who died in Bologna between 1898 and 1944. The personal details associated with the skeletons were cross-checked with the data contained in the cemetery and municipal archives. For each skeleton, the biological profile was assessed using current anthropological methods in order to confirm its correct identification. Four hundred and eighteen skeletons (98.4%), mostly complete and well preserved, are identified at least for sex, and for 95% of these, the age is known. The distribution of sexes in the various age groups is fairly well balanced. The cause of death is known in 93% of the individuals. Approximately 30% of the individuals died from infectious diseases. The occupation is known for more than 92% of the individuals. Most of the women were housewives, while the men were employed in various jobs. The cross-check between archival data with the anthropological analysis of the remains enabled a reliable identification of the skeletons. The sexes and various age groups are well represented, and the sample is substantially uniform as far as geographical origin and socio-economic conditions (lower social classes) are concerned. Thanks to the reliability of the information collected, the Certosa collection is an excellent anthropological tool for the development and validation of osteobiographic methods.