An observational, prospective study was carried out at Hospital Garrahan. Its objectives were to establish the rate of asymptomatic severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among children with cancer and/or their caregivers during hospitalization for chemotherapy, and describe the impact of ongoing treatment among those positive for SARS-CoV-2 or with symptoms compatible with infection during hospitalization. Patients with onco-hematological disease and their caregivers were included. A reverse transcription polymerase chain reaction for SARS-CoV-2 was done. A total of 733 hospitalizations were analyzed. The SARS-CoV-2 positivity rate was 2.2% (95% confidence interval: 1.35-3.52). All patients with a detectable test result completed chemotherapy. Also, 7.7% of patients developed symptoms compatible with a suspected case although they had an undetectable test result, and 77% of them were able to continue treatment.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.