A booster MenC dose induces high SBA and anti Hib response with over 99% of children seroprotected. Children primed with a MenC-TT vaccine reached SBA titers 3.5 times higher no matter which vaccine was used for boosting.
Two telephone surveys were conducted during October 3-11 and December 15-17, 2007 targeting people aged 65 and older randomly sampled by the Computer Assisted Telephone Interview (CATI). Questionnaires were developed under the theoretical framework of the health belief model. Among 1,115 effective samples of pre-survey, 512 (45.9%) were successfully followed.512 people of post-survey were representative of pre-survey population because of their comparability of demographic characteristics. 62.6% (698/1,115) expressed their willingness to receive vaccination and 61.0% (312/512) among post-survey samples actually received vaccination. Important factors influencing their willingness were their beneficial belief in vaccination (OR = 19.8, 95% CI = 10.0-39.2), with obstacles of vaccination (OR = 8.0, 95% CI = 5.0-12.7), awareness of disease seriousness (OR = 1.9, 95% CI = 1.2-3.0). The relevant factors for actual vaccination were living with chronic disease (OR = 2.2, 95% CI = 1.1-4.1), fear of contracting influenza (OR = 3.2, 95%CI = 1.8-5.8, fear of health impairment OR = 3.3, 95% CI = 1.7-6.7, fear of adverse effects of vaccination (OR = 0.2, 95% CI = 0.1-0.3) and unawareness of disease threat (OR = 0.5, 95% CI = 0.30.9).The rate of willingness, approximately to the actual rate of vaccination, and the similar attitude and beliefs on influenza vaccination between two survey population demonstrate the difficulty of conducting propaganda for the elderly. However, target-oriented, focusing relevant factors and selecting appropriate media channels would be the solution for the challenge of high vaccination rate of the elderly.
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