Between 1960-2005, 1,621 cases of tick-borne encephalitis were confirmed by laboratory testing in the region of West Bohemia (now the regions of Pilsen and Karlovy Vary) which represents a rate of infection of 4.1 per 100,000 inhabitants per year. The highest infection rate was established in men aged 20-24 and women aged 45-54. Over the monitored years, there was a significant shift of the maximum infection rate into an older age group. Currently, it is the 45-64 age group which carries the highest rate of infection. Of the identified disease cases, 12 were lethal, which represents 0.7% of the total. Over the years, the risks of transmission in particular areas of the region have changed. The highest infection rate is currently in the district of Klatovy (21.7 per 100,000 inhabitants per year). Of the total number, only two cases were contracted outside the Czech Republic (Slovakia and Austria). In 4.8% cases, the patient's anamnesis showed data on the consumption of non-pasteurized milk. 3.0% of infections probably originated as a result of professional exposure. Over the years, the season of infection has extended. Presently, the transmission can occur anytime between March and November. According to official data, only 6.7% of the population in the Pilsen district has been vaccinated so far. The low percentage of vaccinated cases may, however, in no way influence the unfavorable epidemiological situation regarding tick-borne encephalitis.
37 arc welders were examined; 23 of them had worked for part of the time inside closed cisterns under some of the most hazardous working conditions in Prague where MAC for inert dust was greatly exceeded. Radiographic pulmonary alterations were found in 30 of the subjects. These findings mostly belonged to category i, type s, t, p (according to ILO classification, 1971); only 4 welders from the high-risk group had developed nodulation type m, n, category 2 after an average of 25 years of welding.Statistical comparison of 22 arc welders displaying positive X-ray findings but without chronic bronchitis with a control group of 20 persons of comparable age who were normal in a cardiopulmonary respect revealed no significant differences in lung function.
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