Allergic diseases, such as asthma, allergic rhinitis, eczema, and food allergy, are preventable diseases. Primary prevention strategies of allergic diseases have been in scrutiny. Effective prevention strategies maybe started prenatally, postnatally, during infancy, and even during childhood. These guidelines have been prepared by the Philippine Society of Allergy, Asthma and Immunology and the Philippine Society for Pediatric Gastroenterology, Hepatology and Nutrition. They aim to provide evidence-based recommendations for the dietary primary prevention of allergic diseases in children. The primary audience of these guidelines is all healthcare practitioners who manage patients with potential allergic conditions. These guidelines are based on an exhaustive review of evidences, mostly systematic reviews, randomized controlled trials, and cohort studies. However, there are still many gaps in the evidence of dietary primary prevention of allergic diseases.

Background: The objective of the study was to describe the clinical course of infants with pediatrician-diagnosed gastroesophageal regurgitation (GER), after changing to an infant anti-regurgitation formula. Methods: Information on frequency and volume of regurgitation, and disease progression were collected from mothers of 0-to 12-monthold Filipino infants with GER at baseline and 1 month after a pediatrician prescribed-formula containing carob bean gum, galacto-oligosaccharides and partially hydrolyzed whey protein for 14 days. Results: Eighty-nine infants aged ≤ 6 months and 40 aged 7-12 months old were enrolled. The most frequently reported amount of baseline regurgitation was half of the total feed (29 (33%) younger infants and 17 (43%) older infants). Baseline regurgitation frequency ranged from 1-3 times/day (45 (51%) and 21 (52%)) to 4-6 times/day (33 (37%) and 14 (35%)) and 7-9 times/day (11 (12%) and five (13%)). Regurgitation after 1-day consumption was resolved in 16 (18%) and 8 (20%) and in 57 (64%) and 31 (78%) younger and older infants at 14 days. Forty-one (32%) infants still had regurgitation episodes after a 14-day trial with decreased frequency and volume; three (7%) infants did not show any improvement, while one (1%) infant had increased amount of regurgitation. No medicine was given to study participants. Parent-reported sleep disturbance decreased in three (37%) younger infants and 25 (63%) older infants. Conclusion: Nutrition intervention has effectively improved symptom and quality of life among infants with GER within 14 days. Information on underlying conditions among those with unresolved symptoms are needed.