A401of which were hysterectomies. Before the launch of UPA in France, number of surgeries increased by 380 each year. The introduction of UPA was correlated with a trend reversal, showing a decrease in the number of surgeries of 1,236 each year from mid-2013. UPA did not have an impact on the type of surgery, neither on the surgical approach. The savings associated with the use of UPA pre-operatively (cost of treatment and avoided surgeries included) were estimated at 2M€ in 2013 and will reach 9M€ in 2016, that was considered as a plateau for the following years. The cumulated budgetary impact from 2016 to 2019 is estimated at -37M€ . ConClusions: Thanks to avoided surgeries, the use of UPA as pre-operative treatment is associated with financial savings, which cover largely the treatment costs. PIH10 Budget-ImPact analysIs (BIa) Of tHe IntrOductIOn Of 52mg levOnOrgestrel-releasIng IntrauterIne system (lng-Ius) as a cOntracePtIve metHOd OPtIOn In tHe BrazIlIan PuBlIc HealtHcare system (sus) tO avOId unIntended Pregnancy (uP) In 15 tO 19 year-Old adOlescents
137) of the cases returned negative results, 32% (44) of these patients were irrationally prescribed with anti-malarial drugs sans confirmed diagnosis with injectable artesunate (61%) and chloroquine (32%) for an average of 4 days resulting in 41% overdoses and 38% under doses. Direct cost associated was estimated to be USD 1,167.71. Female bedridden patients with fever and chills ≤ 3 days with normal hematological parameters, liver and renal function tests were more likely prescribed with anti-malarials. These patients had fewer co-morbidities, lower mortality, longer survival rate and longer hospitalization (p< 0.05). ConClusions: Through geriatric pharmaceutical care services, clinical pharmacist can reduce inappropriate prescribing and prevent possible adverse effects without hampering the health related quality of life.
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