It is shown that the drug teraphthal should be considered as a mixture of the octasodium salt of cobalt(II) 2, 3,9,10,16,17,23, and its oxidation product (component A) with the octasodium salt of OCPC and products from the extensive destruction of a substance with a similar elemental composition (component B). The composition can be estimated quantitatively using (i) the results of elemental analysis (H, N, Co) and (ii) PMR in combination with measurement of the weight loss on drying.
A method for quantitative determination of silicon, aluminum, and iron, the main active components in the natural biologically active preparation klimont, is developed that ensures good reproducibility and accuracy. The limits for the content of these elements are established and can be introduced into the "Quantitative Determination" section of the draft manufacturer's pharmacopoeial monograph for klimont.
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