Background:Underreporting of spontaneous adverse drug reaction (ADR) is a threat to pharmacovigilance. Various factors related with the knowledge and attitudes are responsible for underreporting of ADRs.Aims:The study was aimed at investigating the knowledge and attitudes of doctors to ADR reporting.Materials and Methods:It was a questionnaire-based cross-sectional study. One hundred and eight questionnaires were administered to doctors working in a teaching hospital with an ADR monitoring center.Statistical Analysis Used:The descriptive statistics were used for responses to evaluate the knowledge and attitudes toward ADR reporting. Pearson's Chi-square test was used to observe the association of knowledge and attitude with experience and position.Results:The response rate was 62.9%. Spontaneous reporting rate was found to be 19.1%. The major factors found to be responsible for underreporting of ADR include inadequate risk perception about newly marketed drugs (77.9%), fear factor (73.5%), diffidence (67.7%), lack of clarity of information on ADR form about reporting (52.9%), lethargy (42.7%), insufficient training to identify ADRs (41.2%), lack of awareness about existence of pharmacovigilance program (30.9%) and ADR monitoring center in the institute (19.1%), and inadequate risk perception of over-the-counter (OTC) product (20.6%) and herbal medicines (13.2%). Experience and position did not influence the knowledge and attitudes of doctors.Conclusion:The deficiencies in knowledge and attitudes require urgent attention not only to improve the rate of spontaneous reporting, but also for enhanced safety of the patients and society at large.
New data on the photoabsorption spectra of LiH, NaK and KH are reported involving ground state X 1 Sigma and excited state A 1 Sigma near the dissociation limits. Rotational and vibrational analysis of the observed bands is presented: LiH X 1 Sigma V=1 to 1 Sigma (16
New data on the photoabsorption spectra of 7LiH are reported involving the ground state X1 Sigma ( nu =1) and the excited state A1 Sigma ( nu =16 to 26). Rotational and vibrational analysis of the new bands are presented. The highest observed vibrational level approaches the dissociation limit. The estimated dissociation energy is in reasonable agreement with the previously known value.
A five-parameter potential function is proposed for the stable states of diatomic molecules. From a comparison with RKR data it is found that our function is as good as that of Hulburt-Hirschfelder. A three-parameter version of the proposed potential is also discussed
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