High rates of local control are achieved with this SBRT regimen in medically inoperable patients with stage I NSCLC. Both local recurrence and toxicity occur late after this treatment. This regimen should not be used for patients with tumors near the central airways due to excessive toxicity.

No abstract

In the absence of level I data, GTV and histology should be considered to personalize radiation dose for stereotactic ablative body radiotherapy. We suggest lower prescription doses (i.e., 12 Gy × 4 or 10 G × 5) should be avoided for squamous cell carcinomas if normal tissue tolerances are met.

The case records arc reported of 13 patients who gave a history of a well-remembered injury, which appeared to have resulted, within a comparatively short period of time, in the development of a basal-cell carcinoma at the same site. Although it is likely that, if such an injury is relevant, it has only accelerated the appearance of a tumour in a precancerous area, it is, none the less, curious that this happening is more commonly recorded in the pathogenesis of a basal-cell carcinoma than in that of a squamous-cell carcinoma. In seven of the cases the injury was a thermal one.