In the present study, pregnant women with periodontal disease presented an association in the placental tissue between the presence of T. denticola and P. gingivalis and hypertensive disorders. Additionally, increased expression of TLR-2 was observed. However, further studies are required to determine the specific roles of periodontal pathogens and TLRs in the placental tissue of patients with pregnancy-related hypertensive disorders.
Disseminated intravascular coagulation (DIC) can be a rare initial manifestation of adenocarcinoma of the prostate. We present a case in which DIC was the symptom leading to the suspicion of a prostatic tumour. The performance of a prostate biopsy in this situation exacerbated the initial coagulation disorder. This case highlights the risks of prostate biopsy in patients with a suspicion of advanced adenocarcinoma of the prostate. The difficulty of treating DIC in this clinical situation is also discussed.
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