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Autism spectrum disorder is a group of disorders marked by difficulties with social skills, repetitive activities, speech, and nonverbal communication. Deficits in paying attention to, and processing, social stimuli are common for children with autism spectrum disorders. It is uncertain whether eye-tracking technologies can assist in establishing an early biomarker of autism based on the children’s atypical visual preference patterns. In this study, we used machine learning methods to test the applicability of eye-tracking data in children to aid in the early screening of autism. We looked into the effectiveness of various machine learning techniques to discover the best model for predicting autism using visualized eye-tracking scan path images. We adopted three traditional machine learning models and a deep neural network classifier to run experimental trials. This study employed a publicly available dataset of 547 graphical eye-tracking scan paths from 328 typically developing and 219 autistic children. We used image augmentation to populate the dataset to prevent the model from overfitting. The deep neural network model outperformed typical machine learning approaches on the populated dataset, with 97% AUC, 93.28% sensitivity, 91.38% specificity, 94.46% NPV, and 90.06% PPV (fivefold cross-validated). The findings strongly suggest that eye-tracking data help clinicians for a quick and reliable autism screening.

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The proposed method introduces algorithms for the preprocessing of normal, COVID-19, and pneumonia X-ray lung images which promote the accuracy of classification when compared with raw (unprocessed) X-ray lung images. Preprocessing of an image improves the quality of an image increasing the intersection over union scores in segmentation of lungs from the X-ray images. The authors have implemented an efficient preprocessing and classification technique for respiratory disease detection. In this proposed method, the histogram of oriented gradients (HOG) algorithm, Haar transform (Haar), and local binary pattern (LBP) algorithm were applied on lung X-ray images to extract the best features and segment the left lung and right lung. The segmentation of lungs from the X-ray can improve the accuracy of results in COVID-19 detection algorithms or any machine/deep learning techniques. The segmented lungs are validated over intersection over union scores to compare the algorithms. The preprocessed X-ray image results in better accuracy in classification for all three classes (normal/COVID-19/pneumonia) than unprocessed raw images. VGGNet, AlexNet, Resnet, and the proposed deep neural network were implemented for the classification of respiratory diseases. Among these architectures, the proposed deep neural network outperformed the other models with better classification accuracy.