Muscle ultrastructural changes during a typical expedition to the Himalayas were analyzed by taking muscle biopsies from seven climbers before and after their sojourn at high altitude (over 5000 m for 8 weeks). M. vastus lateralis samples were analyzed morphometrically from electron micrographs. A quantitative evaluation was made of lipofuscin, satellite cells and myonuclei. Significant increases of the volume densities of lipofuscin (+ 235%) and satellite cells (+ 215%) were observed.
standard echocardiographic parameters were not predictive of reverse LV remodeling. Conclusions: ECG and EP parameters, evaluating electrical asynchrony at implantation, can predict LV functional recovery and reverse remodeling after CRT. Particularly the use of Bp/RVp index can improve CRT results, by identifying effective pacing sites.
467Cardiac resynchronization in long term follow up: analysis of clinical response predictors
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.