Many infants who represent one of the nosological units that refined functional digestive disorders remain an urgent problem of high frequency of parents' referrals to neonatologists, pediatricians, and general practice — family doctors. Existing studies of a number of hypotheses regarding the etiology, mechanisms of origin, and different approaches to the treatment of colic in infants indicate the relevance of this problem. The article presents current literature data, highlighting the main complaints of parents with suspected colic in a child, presents an analysis of the main causes of this functional bowel disorder, some knowledge about the etiopathogenetic mechanisms of colic, modern components of medical care in infants. Emphasis is placed on the existing ambiguous hypotheses that explain the pathogenetic processes in the body of infants with colic. The focus is on the fact that colic remains a diagnosis of exclusion from other functional bowel diseases. It is noted that the basis of medical support of colic are personalized measures aimed at reducing the severity of pain and choosing the optimal tactics for managing the baby in the period between attacks (background correction), taking into account the existing causes and mechanisms of colic. No conflict of interest was declared by the authors. Key words: functional disorders of digestion refinement, infants, colic in neonate, diagnosis, management.
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