ligand because the smaller molecular forms, which would be better able to penetrate the agarose gel, are not bound, whereas the larger form does bind. The gel can also discriminate between acetylcholinesterase and cholinesterase. This is unexpected because edrophonium is a competitive inhibitor of both enzymes. This suggests that the coupling of a side chain to the meta-hydroxy group of edrophonium alters the inhibitory properties of the molecule.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.