a-Stigmastenol.-A sample (0.3 g.) of the first described benzoate was boiled with 30 cc. of a 5% solution of potassium hydroxide in alcohol for two hours. Water was then added in the sterol extracted with ether. It crystallized from methanol in big leaflets, containing solvent of crystallization. After drying in a vacuum at 80°i t melted at 115°. Mixed with an authentic sample of tt-spinastenol (m. p. 114°) there was no depression of the melting point; [a]23D +24°(24.2 mg., 2 cc. of chloroform, 1=1 dm., h23d +0.29°) in good agreement with the rotation reported for -spinastenol ([<*]d +26).Anal. Caled, for CíjHíoO: C, 83.98; H, 12.16; Found: C, 84.05; H, 12.12.-Stigmastenyl Acetate.-Two-tenths gram of the -stigmastenol just described was heated on the steam-bath with 10 cc. of acetic anhydride. On cooling the acetate came out in the form of big leaflets. It was recrystallized from benzene-alcohol: m. p. 118°, [a]23D + 16°( 18.9 mg., 2 cc. of chloroform, l = 1 dm., a23D +0.15°); no depression with a-spinastenyl acetate (m. p. 117°, [a]d +15°).
S'-Diethylaminoethyl /3-aminocrotonate has been synthesized from ethyl acetoacetate through the sequence: ethyl acetoacetate -jS-chlorocrotonyl chloride -> /S'-diethylaminoethyl ßchlorocrotonate -> /S'-diethylaminoethyl ßaminocrotonate. This ester possessed no local anesthetic activity.
aldehydo-Maltose Octaacetate 1153 somewhat more soluble in organic solvents than the corresponding d-glucoside derivative.The -methyl mannoside was regenerated from this tetracarbanilate according to the procedure of Salmon and Powell* and was identified by melting point and mixed melting point.
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