143ChemInform Abstract Various synthetic pathways for the conversion of the bicyclic enedione (I) into the formyl enone (XII) or related compounds are tested. The reaction route outlined in the scheme proves to be the most convenient method. The key steps are the aminomethylation of the siloxy diene (V), subsequent Hofmann degradation and twofold reduction of the methyleneoctalone (VIII). Hydroxymethylation of the decalone (X) followed by oxidative elimination of the phenyl sulfenyl derivative, gives the aldehyde (XII).
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