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Aim. The aim of this study was to examine the relationship between submaximal and maximal physiological responses to rock climbing for climbers of differing abilities. Methods. Twenty-six male climbers performed a submaximal climbing test on a known circuit at 90° (vertical) and 105° (15° overhanging) inclination and speed 25 movements·min−1. A maximal test was undertaken on a similar circuit at the same speed with inclination increasing by 10° for each successive 3 min stage. Results. Mean oxygen consumption and heart rate (HR) increased with wall inclination and climbers reached a mean (±SD) peak trueV˙Onormal2 of 40.3 ± 3.5 mL·kg−1 ·min−1 during the maximal test. Self-reported climbing ability was negatively correlated with trueV˙Onormal2 and HR during the submaximal test at 90° (trueV˙Onormal2, r = −0.82; HR, and r = −0.66) and at 105° (trueV˙Onormal2, r = −0.84; HR, and r = −0.78) suggesting an increased exercise economy for climbers with a higher ability level. Conclusion. Findings from this study indicate that there is a relationship between wall inclination and the physiological demand of a climb. However, the increased technical ability and fitness of higher level climbers appears to an extent to offset the increased demand through improved exercise economy which in turn leads to an increased time to exhaustion and an improvement in performance.

Markers of systemic inflammation and endothelial dysfunction seem to predict the hypotensive effect of carvedilol on portal hypertension in patients with liver cirrhosis and may be useful in the assessment of the efficacy of the therapy.

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