heated. The steam alone is used for the distillation. One hundred cc. of distillate is collected. To this 100 cc. of distillate, placed in a 200 cc. round bottom flask, are added 7.5 Gm. of potassium dichromate and 15 cc. of concentrated sulfuric acid. The flask is connected to a long, well cooled condenser by means of a Hopkins distilling head. The contents are well mixed. A medium sized (\l/2 inch) Bunsen flame is applied, so that the distillation is not too rapid. The distillation should be at a slow but constant rate. It should take about sixty minutes to collect the required 80 cc. of distillate. When exactly 80 cc. has been collected, the distillate is well mixed and aliquot portions are titrated with 0.05 normal sodium hydroxide for the acetic acid produced. A small part of this distillate should be tested for the sulfate ion in order to be sure that no sulfur trioxide has passed into the distillate. If this procedure is followed, there should be absolutely no danger of sulfur trioxide being distilled. From the amount of acetic acid found by titration, the amount of ethyl alcohol is calculated as follows :13 Per cent alcohol = (cc. of 0.0S normal alkali needed for entire 80 cc. of oxidized distillate -0.42) x 0.027. By means of the methods described, 3,471 highway fatalities of all types covering a period from Jan. 1, 1928 to Dec. 31, 1937 were investigated. All cases were analyzed for methyl (wood) alcohol and, if it was present, were not included in this report. During this decade 6,911 necropsies were performed in a total of 12,897 highway deaths. The patients on whom tests were not made, and hence were not included in this
In 50 patients with ischaemic heart disease prospective analyses of the reproducibility of exercise tests at 3-month intervals were performed. The same method of testing was used repeatedly in a smaller group of patients 3 or more times at 6- to 8-week intervals. No significant differences were found in maximal heart rate, maximal systolic blood pressure, rate-pressure product, and total work. Symptoms resulting in the discontinuation of exercise were unchanged in 94 per cent of patients. The evaluation of the electrocardiographic recordings revealed good agreement in 94 per cent of patients. The evaluation of the electrocardiographic recordings revealed good agreement in ST segment depression and ST segment elevation. The reproducibility of arrhythmic events was very poor. The standardized electrocardiographic exercise test is, therefore, recommended for objective evaluation of various interventions in patients with manifest ischaemic heart disease, both in short-term and long-term follow-up studies.
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