s153 sensitivity analysis was done using a Montecarlo simulation with 1,000 iterations, furthermore, an univariate sensitivity analysis was estimated by a tornado diagram. Results: The effectiveness obtained after the adjustment (proportion of IAI cases successfully treated) was 89% for ertapenem, 73.6% for piperacilin/tazobactam, and 86% for ceftriaxone/metronidazole.
s149 and computed the differences between treatment groups as change from baseline to end of follow up, 95% confidence interval (CI). Results: Overall, 555 abstracts were identified and screened, of which seven RCTs that enrolled 388 patients published in English language between 2011 and 2016, met our inclusion criteria. The mean age of participants ranged from 10.3 to 48 years. Duration of interventions ranged from 12 to 48 weeks. Various dose of Vitamin D doses ranging from 7000 to 100,000 IU, with different dosing frequencies were compared to placebo or active comparator. All included studies showed low risk of bias. The meta-analysis results showed that vitamin D therapy compared with control, increased percent naïve CD4: 6.9 (95% CI: 1.35 to 12.51); decreased viral load (copies/mL): -758.00 (95% CI: -1100 to -405.35); decreased total cholesterol: -14.62 (95%CI: -17.92 to -11.32); decreased LDL cholesterol: -15.00 (95% CI: -17.95 to -12.05). Findings on serum glucose, insulin levels and HDL cholesterol, were not statistically significant. There was no data on mortality and HRQL. ConClusions: The current evidence suggest that vitamin D supplementation among HIV/AIDS patients appear to increase CD4 count, decrease viral load and improve serum lipid profile.
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