The intact globe expansion method (GEM) imposes a loading geometry comparable to in vivo conditions and can quantify changes in mechanical stability as a function of testing conditions (e.g., IOP, tissue maturation, and therapeutic cross-linking) with small sample sizes and small variability. Rabbit kit eyes provide a model of weak tissue suitable for screening treatments that strengthen the cornea and sclera.

Rheumatoid arthritis (RA) is a disease characterised by joint deformity and subluxation. Although many joints may be involved, dislocation of the manubriosternal joint is extremely rare. A case of dislocation of this in a woman with RA is presented. Case report The patient, a 62-year-old woman, first presented to this hospital in September 1979 with an acute exacerbation of chronic obstructive airways disease. She gave a history of pernicious anaemia treated with monthly injections of vitamin B12 and of longstanding rheumatoid arthritis (RA) treated with