Aim: The present study was done to determine the activity of Naturally prepared licorice mouthwash in comparison to chlorhexidine mouthwash. Introduction: Maintenance of oral hygiene is very important in preventing the growth of a sticky film of bacteria and food particles that accumulates on teeth and hence Mouthwashes are prescribed in dentistry for treatment of several oral conditions and for prevention against various microorganisms. Licorice is derived from "liquiritiae” which is shrub or herb and the yellow colour of it is due to the flavonoids content of the plant, which includes liquiritin, isoliquiritin and other compounds. Herbal Mouthwashes (mouth rinses) are solutions or liquids intended to reduce the microbial load in the oral cavity. Materials and Methods: This study was conducted in Saveetha Dental Hospital, Chennai, Tamilnadu, India. The liquorice was extracted and formulated as mouth wash. Fig. 1 denotes the salivary samples were obtained from 20 volunteers (10 test group, 10 control group) and then, the participants were asked to rinse their mouth with freshly prepared licorice mouthwash(test group), chlorhexidine mouthwash (control group) and then paired saliva samples were obtained immediately after and before the mouthwash and finally the Colony forming units were recorded for pre and post usage of both the herbal and commercially available mouthwash. Results: Study showed that there was a mean reduction in the colony-forming units with herbal mouthwash and Chlorhexidine mouth washes. Herbal mouthwash showed reduction in colony forming growth after usage of herbal mouthwash.
Introduction: Boerhavia diffusa (Mukkirattai) of the Nyctaginaceae family is a widely used folk medicinal plant that grows as a common weed with its leaves, seeds and roots are useful parts with pharmacological activities with a cure for twenty-three ailments. Phytochemical constituents of B.diffusa showing antimicrobial activity includes phenols, flavonoids, tannins, saponins, alkaloids, glycosides. Aim: The present study aimed to evaluate the qualitative analysis of the antimicrobial activity of aqua alcoholic extracts of Boerhaavia diffusa L. (Family: Nyctaginaceae) leaves. Materials and Methods: Boerhavia diffusa (Mukkirattai) was freshly procured as a powdered form from different solvent extracts that were tested against the Gram-positive bacteria and fungal strains by observing the zone of inhibition which showed the antimicrobial activity of Boerhaavia diffusa L. Staphylococcus aureus, Enterococcus faecalis, Streptococcus mutans and fungal strains Candida albicans were used in this test. The obtained data were analyzed statistically by Non parametric Spearman correlation analysis. Results: Antimicrobial activity was observed in the aqueous-alcoholic extracts against Gram-positive bacilli, cocci and fungal strains. The aqua alcoholic extract of B. diffusa showed positive correlation with p value less than 0.05 with antimicrobial effect against fungal strains (e.g. C. albicans which had a zone of inhibition diameter of 26mm) and with Gram-positive bacteria (e.g. Staphylococcus aureus showed inhibition diameter of 20 mm), with Gram Positive cocci (e.g. Streptococcus mutans showed an inhibition diameter of 18 mm) when compared to Enterococcus faecalis. Conclusion: The Aqua alcoholic extract of Boerhavia diffusa being biofriendly and inexpensive has a very strong Antimicrobial activity against Candida albicans and Staphylococcus aureus while it showed minimal antimicrobial activity against Streptococcus mutans and Enterococcus faecalis.
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