Introduction: Early detection of oral cancer by diagnosing the precancerous lesions is the best way for controlling and decreasing cancer’s mortality. Dentists have a significant role in early detection of precancerous lesions and their capability to detect is highly subjected to their levels of knowledge about these lesions. The aim of this study was to assess the level of knowledge, attitude and practice of general dentists in Yazd City regarding oral precancerous lesions. Methods: In this cross-sectional study, 180 Yazd general dentists, were selected and they completed a questionnaire, which was consisted of two parts: demographic information and questions referring the knowledge, attitude and practice; data were analyzed using SPSS 16 software and ANOVA and T-test. Results: Mean score of knowledge was 13.38 ± 2.49 from maximum 22 and mean score of attitudes was 19.35 ± 1.72 from maximum 21, which implies that the participants have a better attitude. No significant correlation was reported between knowledge and gender, years of graduation, workplace, work experience, and attending in retraining classes (P. -value=0.255). There was a significant correlation between attitude and years of graduation (P-value=0.056), which means that participants with 5 years of graduation or less had better attitude toward precancerous lesions. Conclusion: General dentists of Yazd City have an average knowledge but a good attitude towards precancerous lesions of mouth. Regarding their practice, more than 50% of the participants referred to the orthopedic specialist in case of precancerous lesions.
Background: Severe dry mouth can be the leading cause of bacterial sialadenitis by Staphylococcus Aureus (SA) as the most causing bacterial agent. Both of the Beta-lactamase Penicillins and the first-generation of Cephalosporins have been suggested as a treatment of the choice in such these conditions. The purpose of this study was to compare the minimum inhibitory concentration of Cephalothin and Oxacillin against the SA by E-Test method. Methods: In 62 Sjogren's patients, Sampling was done from the right parotid gland and the samples were sent to the lab within two hours. After certain microbial lab procedures (culture, SA identification and isolation), Positive samples for SA were collected and Minimum Inhibitory Concentration (MIC) was measured in each sample for both Cephalothin and Oxacillin by detecting eclipse around E-Test strips. Also MIC50 and MIC90 of these two antibiotics were recorded. The data were coded by SPSS16 and statistical analysis between two groups was done by Paired T-Test. Results: SA was isolated from 30 patients (48%). The difference between the average MIC of these two antibiotics was significant (P=0.001). The correlation coefficient between variables was 0.821, which was significant (P<0.0001). MIC 50 of Oxacillin was less than Cephalothin. It was the same for MIC 90. Antibiotic resistance was found in 3% of the patients. Conclusions: The average MIC in Oxacillin was less than Cephalothin. In other words, Oxacillin was more effective than Cephalothin.
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