Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a life-threatening adverse drug reaction if it is not timely diagnosed and treated. This happens probably following a cascade of immune reactions after the administration of the drug ultimately leading to multiorgan failure and death. Several groups of drugs have been identified as potential aetiologies but the commonest one identified is antiepileptic drugs. The clinical features of DRESS syndrome usually appear several weeks after commencing the offending drug. Initially, fever lymphadenopathy and rash appear followed by hepatitis. Rash is the most prominent feature, and it is a generalized erythematous nonblanching maculopapular rash without the involvement of the mucus membranes or eyes. The rash desquamated over the following days and changed it’s context to an exfoliative dermatitis. We report a case of a 10-year-old boy who is one of the twins born to nonconsanguineous parents at 34 weeks of gestation.
Introduction: One of the main risk factors of obstructive sleep apnoea (OSA) is childhood obesity which account for about 60% incidence in obese children. Although polysomnography is the gold standard, it is costly and difficult to be used in children. The objective of this study was to use a prediction tool called a "Modified STOP bang tool" in the assessment of OSA in overweight and obese children in Southern Sri Lanka.
Methods:A descriptive cross-sectional study was conducted on ninety seven children ( 57boys) aged 5 -15 th years with BMI >85 percentile for age and gender based on CDC 2000 growth charts recruited from the nutrition clinic at the Teaching Hospital, Karapitiya, Sri Lanka. Modified STOP bang questionnaire th th which assessed snoring, tiredness, observed apnea, blood pressure 95 percentile, BMI >95 percentile, th academic problems, neck circumference >95 percentile for age, and male gender was considered on all study participants and a score was generated. Results: Out of 97 children participated, 27.8% children had a higher risk of OSA and 49.5% had an intermediate risk of OSA. According to this study, significant risk factors for OSA in overweight and th obese children included, being a male, BMI greater than 95 percentile for age, obesity for age and sex, th circumference greater than 95 percentile for age, neck/ height ratio and waist/hip ratio.
Conclusion:In the community setting, modified STOP bang questionnaire is useful in the screening of overweight and obese children for OSA and for further follow-up.
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