D e r m a t o f i b r o s a r c o m a p r o t u b e r a n s :review of 20-years experience J a i m e R u i z -T o v a r a, M o n t s e r r a t F e r n f i n d e z G u a r i n o b, M a r i a E u g e n i a R e g u e r o C a l l e j a s c, A s u n c i 6 n A g u i l e r a Velardo% J u a n A r a n o B e r m e j o ~ a n d L u i s C a b a f i a s N a v a r r o a aDepartment 6 0 6 Fig. 1. Reddish-brown coloured papule with ulceration. Clin TraJ~sl OJ~col. 2006;8(8):606 I0 RUIZ-TOVAR J, FERN~,NDEZ GUARINO M, REGUERO CALLEJAS ME, AGUILERA VELARDO A, ARANO BERMEJO J, CABANAS NAVARRO L. DERMATOFIBROSARCOMA PROTUBERAN,.q: REVIEW OF 20 YEARS EXPERIENCE

Photodynamic therapy (PDT) treatment for multiple actinic keratosis (AK) has been found effective when lower doses of red light were used with methyl aminolaevulinic acid (MAL). The aim of this study was to compare the results of lower doses of red light conventional PDT (h-PDT, 16 J/cm2) with MAL and aminolaevulinic acid (ALA) in a long-term follow-up. Patients with more than five symmetrical AK on the scalp who were candidates for PDT were selected and divided randomly between MAL and ALA treatment and patients were followed at 3 and 12 months. The responses were assessed by counting the total AK and the AK per patient. Pain and adverse events were also compiled. A total of 46 patients were treated, 24 with MAL, and 22 with ALA. The two groups were comparable at baseline (p > 0.005). No significant differences were found in the results of both treatments at 12 months, despite ALA exhibiting slightly better results at 3 months. No differences in pain and adverse events were assessed. Both ALA and MAL were effective when lower doses of red light were used in c-PDT. Long term efficacy was also documented. Further studies are necessary to determine the inferior point of red-light illumination without losing efficacy.

Background: Photodynamic therapy (PDT) is a treatment for non-melanoma skin cancer. In recent years, its use has expanded to new indications. Viral warts (VW) are some of the most promising. Methods: A retrospective, descriptive, observational study was carried out. Patients who did not respond to cryotherapy were selected and were occluded with methyl aminolevulinate (MAL) for three hours and they were illuminated with red light. Tolerance to treatment was evaluated using a visual analog scale for pain (from 0 to 10). Results: A total of 15 patients with 134 VW were treated. A complete response was obtained in 13 of 15 patients (87%) and in 127 of 134 lesions (95%). The mean number of sessions was 3.1 (range 1 to 6) and the average pain score was 3.1 (range 0 to 8). Conclusions: PDT is a treatment that offers good results in the treatment of VW that are resistant to routine treatment. The treatment was well tolerated in our patient group.

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