Obstructive sleep apnea is a chronic condition characterized by frequent episodes of upper airway collapse during sleep. Collapsibility can be increased by underlying anatomic alterations and/or disturbances in upper airway, neuromuscular control, or both, which play key roles in the pathogenesis of obstructive sleep apnea. Neurofibromas of the parapharyngeal space are the second most commonly encountered primary tumor of the nerve sheath origin. A parapharyngeal neurofibroma of the cervical sympathetic chain, presenting as obstructive sleep apnea with all the features mimicking that condition is reported here for its rarity in modern clinical practice. A transcervical approach was adopted to excise the tumor in toto, following which patient was completely relieved of the symptoms, especially those of respiratory distress and features of OSAS.
Almost all organs systems in the body are under the influence of autonomic nervous system (ANS) for maintaining homeostatic regulatory functions. Many of the present lifestyle related disorders like hypertension and obesity have their primary pathology in the homeostatic derangements. Childhood overweight and high blood pressure increase the risk of subsequent obesity and hypertension in adulthood. To the best of our knowledge there is no sufficient qualitative and quantitative data in childhood which restricts the use of this tool in scientific medical practice and in understanding the occurrence of these systemic diseases in near future. The plan of our study is to assess the classical cardiovascular autonomic functions tests in school children and to generate normative data to validate the subtle variations present in childhood for an earlier intervention.
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