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This sample of Iranian children shows high rates of overweight at young ages but also high rates of breast-feeding. The duration of breast-feeding is inversely related with the prevalence of overweight in pre-adolescent children.

Background: Low birth weight (LBW) is one of the major determinants of neonatal survival as well as postnatal morbidity. Objective: The main objective of the present study was to determine neonatal mortality rate (NMR) in LBW infants in Yazd, Iran. Materials and Methods: In a prospective-cohort study, all births in the maternity hospitals of Yazd, Iran in 2004 were evaluated and mortality rate in LBW population over the course of the first month of extra uterine life was determined. Results: In total, 8.4% (507 of 6016 births) of all newborns were LBW and 18.7% (95/507) of all LBW neonates died. Neonatal mortality rate in Yazd was 24/1000 live births .Two-third (95 /143) of all neonatal deaths occurred in LBW. Neonatal mortality rate (NMR) in LBW, Moderately low birth weight (MLBW), Very low birth weight (VLBW) and Extremely low birth weight (ELBW) were 23, 11.5 , 62.5 and 117 times more than that of normal weight newborns, respectively. Nearly 65% of all LBW neonatal deaths occurred in first 24 hours after birth. Overall NMR, Early Neonatal mortality rate (ENMR) and Late Neonatal mortality rate (LNMR) in LBW were 187, 118 and 9.8 in 1000 live births, respectively. The main causes of mortality among LBW in order of prevalence were respiratory distress syndrome (RDS) (59%), asphyxia (20%), septicemia (12%) and congenital malformation (9%). Conclusion: Neonatal mortality rate in Yazd is high and LBW accounted for two-third of neonatal deaths. Therefore, effort should be intensified to implement effective strategies for the reduction of LBW births and improving the care of these vulnerable neonates.

Introduction: At present, about 1% of newborns are delivered through assisted reproductive technologies (ART) worldwide. This study aimed to evaluate and compare the growth parameters of children born in assisted and natural conception at 5 years of age. Materials and Methods: In a cross-sectional case control study, weight, height and head circumference of 5-year old children were assessed. The case group consisted of term, singleton babies who were products of ART in the Center for Infertility of Shahid Sadoughi University, Yazd, Iran in 2005. The control group consisted of term, first child, singleton and spontaneously conceived 5-year-old children who were referred for vaccination to primary health care center of Shahid Akbari in 2010. Results: Fifty-eight girls (47.5%) and 64 boys (52.5%) “with equal numbers in each of the 2 groups” were evaluated. Sex distribution, mean ages of fathers and mothers were not statistically significant different in both groups. Children born after ART tend to have lower birth weight, smaller birth head circumference and lower weight at 5 years of age. Having low birth weight (<2500 g), being underweight and having short stature at the age of 5 were more common in babies born through ART. Conclusion: Growth retardation is more prevalent in babies born through ART. Thus, growth assessment, parents’ knowledge about child physical development, and timely and accurate follow-up of these children are necessary for early detection of any growth disorders. Key words: ART, Growth, Height, Natural Conception, Weight

Objective: To compare a dose of oral and rectal acetaminophen and to evaluate acceptability of rectal acetaminophen, since oral and rectal acetaminophen is widely used as an antipyretic agent in febrile children and the comparative effectiveness of these two preparations is not well established. Methods:In this prospective parallel group designed study, 60 children who presented to the emergency department or outpatient pediatric clinic at a tertiary hospital and aged from 6 months to 6 years with rectal temperature over 39 °C were enrolled. Patients were randomly assigned to two equal-sized groups. Group 1 received 15 mg/kg acetaminophen rectally and group 2 received the same dose orally. Temperature was recorded at baseline and 1 and 3 hours after drug administration. Results:In the first group, mean decrease in temperature, 1 and 3 hours after administration of acetaminophen was 1.07±0.16 (p < 0.001) and 1.74±0.25 °C (p < 0.001), respectively, and in the second group it was 1.98±0.19 (p < 0.001) and 1.70±0.14 °C (p < 0.001), respectively (p > 0.05). Conclusion:Rectal and oral acetaminophen preparations have equal antipyretic effectiveness in children. The rectal route proved to be as acceptable as the oral one among parents. J Pediatr (Rio J). 2010;86(3):228-232:Oral acetaminophen, rectal acetaminophen, fever.

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Background:One important feature of influenza viruses is the high rate of mutation in the virus coat proteins, hemagglutinin and neuraminidase. These viruses are related to RNA viruses and belong to the family Orthomyxoviridae. Virus antigenic variations are called antigenic drift or minor changes and antigenic shift or widespread changes. The large pandemic of influenza is usually caused by virus antigenic shift. A new form of the influenza virus is called influenza virus A (H1N1). Objectives: The purpose of our study was to investigation of the relationship between demographic characteristics and frequency of mortality in certain cases of influenza A (H1N1) from the Yazd Province of Iran. Materials and Methods: We referred to a health center of the Yazd province to collect characteristics and information related to patients during years2008 -2009. This study was descriptive and analytical. Out of 1442 patients suspected of influenza during the study period, 253 throat samples had positive with RT-PCR (reverse transcriptase-polymerase chain reaction) results, which were confirmed for viruses. After obtaining the names and contact numbers of these patients, their information and data were recorded in the Excel program and then were analyzed using the SPSS software and chi-square statistical method. Results: Out of 253 cases confirmed for influenza A (H1N1), 9 women and 11men had died. Amongst these cases the minimum and maximum age was3.5 and90 years, respectively. Also, from the 20 confirmed cases of influenza A (H1N1) that had died, 16 cases had at least one underlying disease. Conclusions: There was no significant association between mortality of confirmed cases of influenza A (H1N1) and sex, but the results demonstrated that mortality may be associated with age and underlying diseases.