-Some preliminary results are provided towards the study of the violation of genomic super-symmetry; that latter is the so called Second Chargaff's rule. The rule stipulates that oligonucleotides that could be read equally in opposite directions with respect to the symbol change according to the complimentary law (complimentary palindromes) should exhibit pretty close frequency. We have checked the genomes of organisms of various taxa ranging from viruses via bacteria, yeasts, animals, plants, etc.; more than 1500 genetic sequences had been studied, totally. The measure for the second rule violation was calculated for a single strand. Both intragenomic, and intergenomic studies have been carried out. It was found that intragenomic variability decays, as the length of string grows up. The intergenomic variability is comparable to the intragenomic one, for considerably short strings.
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