No abstract

Cloacal exstrophy is a rare congenital malformation resulting from midline abdominal and pelvic defects that is characterized by omphalocele, exstrophy of the bladder, imperforate anus, and vertebral abnormalities. We report an unusual case of monozygotic twins concordant for cloacal exstrophy, detected during antenatal ultrasound scanning. We present the frequency, embryological origin, diagnosis, and prognosis of this condition. CASE REPORTA 29-year-old woman, gravida 3, para 2, with an uneventful past medical history, was transferred to our institution at 22.5 weeks, menstrual age (MA) for evaluation of a complex malformation.

The loss of middle cerebral artery compensatory vasodilatation appears to be ominous in fetuses with absent end diastolic umbilical waveforms. The authors report a case with a loss of the ‘brain-sparing effect’ 24 h before fetal death. Current pathophysiological explanations are discussed.