The journal of Toxicology and pest control is one of the series issued twice by the Egyptian Academic Journal of Biological Sciences, and is devoted to publication of original papers related to the interaction between insects and their environment. The goal of the journal is to advance the scientific understanding of mechanisms of toxicity. Emphasis will be placed on toxic effects observed at relevant exposures, which have direct impact on safety evaluation and risk assessment. The journal therefore welcomes papers on biology ranging from molecular and cell biology, biochemistry and physiology to ecology and environment, also systematics, microbiology, toxicology, hydrobiology, radiobiology and biotechnology. www.eajbs.eg.net
In this study, we have compared the effects of sub-lethal concentrations of clothianidin (Supertox 48% SC) and Spinoza (Tracer 24% SC) on mortality percent, brood lock, C-shape and foraging behavior of first Carniola and Italian hybrids honeybee larvae in hive. The ingestion food was contaminated with the tested insecticides at concentrations of 0.00, 0.001, 0.005, 0.01, 0.05 and 0.1 ppm. Results revealed that the two tested pesticides at hive-residue levels triggered increase in larval mortality according to untreated larvae after 7 days of exposure. Moreover, hybrids Carniola and Italian honeybees' larvae were more sensitive to Spinosad compared with 88.89% and 75.00% mortality after 7 days, respectively, while the corresponding values with clothianidin were 72.22% and 50.00% for both hybrids honeybee' larvae, respectively.
The overall purpose of this work is to throw some light on the acute oral toxic effects of three commercial formulations of chlorpyrifos (i.e. Dursban, Pyriban and Chlorzan) 48% E.C. and cypermethrin (Sparkil 25% E.C.) and the mixture of Dursban and Sparkil on adult male and female albino rats. All the tested formulations were administered in corn oil to the rats and the median lethal doses (LD50 values) were determined after 24, 48, 72 and 96 hours (hrs) of treatment.The obtained results revealed that the oral LD50 values of the tested insecticide formulations (Dursban, Pyriban, Chlorzan and Sparkil) on adult male and female rats were (125, 115), (100, 94), (140, 103) and (387, 251) mg/Kg body weight (b.w.) after 24 hrs, respectively. The 48hrs oral LD50 values of the fore mentioned formulations were (112, 90), (100, 75), (126, 81) and (230, 206) mg/Kg b.w., respectively.On the other hand, the acute oral toxicity of the mixture of Dursban and Sparkil was considerably higher than the acute toxicity of each of them since the acute oral LD50 values were 102 and 75 mg/Kg b.w. for male and female rats after 24hrs, respectively.
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