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Highlights Nearly 75 % of the survey respondents indicated that they were likely to accept COVID-19 vaccine. 48 % of the survey respondents were likely to accept to participate in a vaccine clinical trial if asked against SARS-CoV-2 infections. Healthcare workers were more prone to get vaccinated against COVID-19 than non HCWs.

Background: Antidepressants are heavily prescribed drugs and have been shown to affect inflammatory signals. We examined whether these have anti-inflammatory properties in animal models of septic shock and allergic asthma. We also analysed whether antidepressants act directly on peripheral cell types that participate in the inflammatory response in these diseases.