Whey, the natural product resulting from coagulation of milk is reported to have diverse pharmaceutical credentials. In the present investigation the anti-diarrhoeal activity of the whey powder was investigated. The Whey powder which was prepared using rennet powder and lactic acid, was studied against Magnesium sulphate-induced Diarrhea in Swiss Albino mice. Castor oil-induced enteropooling studies and in vitro biofilm-forming potentials of the whey powder were also carried out, as this is believed to contribute to the anti-diarrhoeal activities of the preparation. Anti-diarrhoeal activity was more pronounced in mice which received 250 mg kg b.wt. of whey powder when compared to those which received 500 mg kg(-1) b.wt. The percentage inhibition of total number of feces in the 250 mg kg(-1) b.wt. drug-treated group was 56.14%,whereas the animals which received 500 mg kg(-1) b.wt. of whey powder showed 37.18% inhibition. The loperamide treated animal group showed 63.81% inhibition. In castor oil induced enteropooling, the percentage inhibition of intestinal content in the 250 mg kg(-1) b.wt. drug-treated group was 61.42% against atropine-treated animal group that showed 26.24% inhibition. The whey powder also exhibited strong biofilm forming capacity with increase in concentration. The anti-diarrhoeal activity of whey preparation established herein is believed to be owing to certain active principles present in it or due to biofilm-forming capacity, which inhibits the attachment of mediators of diarrhoea to mucosal walls of the GI tract or due to interaction of diarrhoea inducing chemicals with whey peptides, which needs further investigation.
From a technical and commercial point of view it is found that electronic sensing technologies have emerged significant progresses over the last few decades. The potentiality of reproducing human senses by sensor arrays and pattern recognition systems is termed as electronic sensing. E-Nose provides an industry-specific management resolution for the perpetual and real-time monitoring of environmental odor and air quality resulting in higher profit and improved community relations. The device constitutes arrays of effective and rapid acting chemical sensors, supplemented by patented electronics and software. Chemicals in the air are identified by the sensor arrays, registering complex odor images in real time. By means of wireless connection or lines a permanent record is sent to the computer, where it is detected, computed and alarms for inconsistent events were sent or else it can be indicated by some displacement. Electronic nose instruments are exploited by research and development laboratories, quality control laboratories, process & production department's of environmental protection, all these are done for the detection of volatile organic compounds in air, water and soil samples, and the measurement and comparison of the effects of manufacturing process on products are also determined. In this paper, An E-Nose is proposed to identify the gas component. For this process, the soft computing technique called Genetic algorithm is used. This provides an optimized weight to identify the gas component by means of the input concentration range and SMAC/hr (units in ppm). The intended Technique is evaluated with different training samples and results are produced.
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