Abstract. The effect of propranolol on the induction of endocrine and exocrine pancreatic function by secretin (SC) and cholecystokinin‐pancreozymin (CCK/PZ) was investigated in 35 metabolically normal subjects. Insulin secretion could be inhibited by propranolol after administration of glucose or SC. On the other hand it was not possible to inhibit the CCK/ P2 induced insulin secretion by propranolol. Exocrine pancreatic function was not influenced by the administration of propranolol. Our results suggest that the action of SC on the islet system, like that of glucose, is linked to the β‐adrenergic system.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.