For the period of 2019, magnetic resonance imaging of the head of patients aged 20–71 years was performed. The majority of males have mezocran the shape of the skull, in contrast to females. There was no universal type of pneumatization for both sexes. In young men, the sellar type prevails, but at the age of 60, this type is 2 times less common and there are no protrusions of the channels of the optic nerves and internal carotid arteries. However, only the protrusion of the internal carotid artery channel is more common in women over 60 years of age than in men. In men, there were no cases of canal protrusion, and 49% of young women had a depression in the wall of the sphenoid sinus. In men under the age of 60, the protrusion of the optic nerve channels and internal carotid arteries occurs in approximately the same way as in women over 80 years of age. Due to the variability of the anatomical configuration of the sphenoid sinuses, the impact on access to the cell through the nose can be serious. The surgeon must be aware of these results before surgery in order to reach the cell safely and effectively.

The coronavirus disease COVID-19 began to spread worldwide in December 2019 from the city of Wuhan (China). COVID-19 is often accompanied by fever, hypoxemic respiratory failure and systemic complications (for example, gastrointestinal, renal, cardiac, neurological, and hepatic lesions), thrombotic phenomena. Central nervous system damage is caused by the primary effect on it, direct neuroinvasion of the virus, and more often by secondary effect due to systemic hyperinflammation. Neurological manifestations include fatigue, headache, insomnia, and olfactory/taste disorders. Neurological manifestations and complications of COVID-19 are diverse: (1) cerebral circulatory disorders, including ischemic stroke and macro/microhemorrhages; (2) encephalopathy; (3) para/postinfectious autoimmune complications, such as GuillainBarre syndrome; (4) meningoencephalitis; (5) neuropsychiatric complications (psychosis and mood disorders). In terms of pathogenesis, neurological disorders in COVID-19 can be caused by neurotropicity and neurovirulence of SARS-CoV-2, cytokine storm, hypoxemia, homeostasis disorders, as well as their combined effects. COVID-19 adversely affects the course and prognosis of chronic neurological disorders in comorbid patients. The review highlights the need for vigilance to early neurological complications in patients infected with SARS-CoV-2 and other coronaviruses, especially since some neurological complications may precede respiratory manifestations.