Objectives: To investigate the presence of toxoplasmosis, rubella, cytomegalovirus, and herpes (TORCH) infections in women attending at the antenatal care clinic in Abha, Kingdom of Saudi Arabia (KSA). Methods: A total of 190 blood samples were collected from Abha maternity hospital in Aseer region, KSA, from February 2018 to May 2019 and screened with the TORCH panel (toxoplasmagondii [IgG/IgM], cytomegalovirus [CMV] [IgG/IgM], rubella [IgG/ IgM], and herpes simplex type 1 and 2 [IgG/IgM]). Results: The mean age was 31.42±6.514 years and gestational age was 32.48±6.168 weeks. Serum IgG was positive for Toxoplasma gondii (T. gondii) (27.4%), herpes simplex type 1 (HSV-1) (94.7%), herpes simplex type 2 (HSV-2) (0.5%), CMV (100%), and rubella (88.9%). Serum IgM was positive only for CMV (9.5%). Though, there was an association between abortions from previous pregnancies (26.5%), intrauterine death (5.8%), premature labor (3.2%), microcephaly (1.6%), other congenital diseases (1.6%) and low birth weight (0.5%) with current IgG positivity for TORCH infections, the results were not statistically significant. Conclusion: Seropositivity for IgG antibodies correlate with TORCH-associated pregnancy complications in Abha, KSA; however, IgM positive CMV pregnant cases warrant further systematic investigation to understand the implications of CMV on outcomes during pregnancy.

To determine the incidence, characteristics of patients and identified the risk factors, and maternal and fetal outcomes of uterine rupture at KAUH. Materials and Methods: Retrospective analysis of 51 cases of uterine ruptures (KAUH), from January 2011 to December 2015. Variables (age, gravidity, height, BMI, risk factors, previous C/S, previous abortion antepartum hemorrhage (APH), postpartum hemorrhage (PPH), gestational diabetes mellitus (GDM), smoking, multiple pregnancies, educational level >12 years, induction and method, mode of delivery, gender, fetal weight, neonatal NICU, and death and maternal outcomes. Ethical approval obtained. Inclusion criteria were all women admitted due to labor that had a ruptured uterus and managed at KAUH. Results: In a total of 20,568 deliveries, uterine rupture occurred in 51 cases (incidence of 0.03%, 1:403), scarred vs. unscarred was 1:514, and 1:1870, respectively. Age was 21 to 46 years, with a mean of 32.69 ± 5.59 years. There were two primigravida (3.9%), 27 multigravida (52.9%), and 22 grand multigravida (43.3%). Thirty-nine (76.5%) underwent emergency C/S, three (5.9%) delivered by spontaneous vaginal delivery, and 24 patients (47.1%) had received maximum eight units of packed red blood cells. One patient underwent a hysterectomy, and five women were admitted to the ICU. Hospitals stay was from three to nine days. Nine babies had Apgar score ≤ 6 at one minute, admission to NICU included nine (17.6%) babies. Neonatal death occurred in five (6.1%) babies. Conclusion: Incidence uterine rupture is low 0.03 % in the present institution. Scarred uterus ruptured more frequently than unscarred. Risk factors include age > 35 years, gravidity > 4, past history of C/S, level of education less than 12 years, and significant neonatal morbidity.