This study compared the efficiency of a five-day or standard (nine-day)
progesterone-based regimen combined with equine chorionic gonadotrophin (eCG) in a
fixed-time AI (FTAI) protocol for dairy cows. The data examined were derived from
3577 inseminations conducted in three dairy herds. Animals with no estrus signs
detected over 21 days were randomly assigned to a PRID-9 or PRID-5 group. Cows in
each group received a progesterone intravaginal device (PRID) for 9 or 5 days,
respectively, PGF2α and eCG on PRID removal, and GnRH 48 h later.
Fixed-time AI was performed 12 h after the GnRH dose. Cows artificially inseminated
following spontaneous estrus during the study period were considered as controls.
Based on the odds ratio, the likelihoods of animals in PRID-9 in the warm (conception
rate [CR] of 22.3%) and cool (32% CR) periods, and control animals in the warm period
(26.6% CR) becoming pregnant were reduced (by factors of 0.6, 0.3 and 0.4,
respectively) compared with the control animals in the cool period (CR of 43.7%). The
risk of a twin pregnancy was higher (51.4%) for cystic PRID-9 cows (by a factor of
3.6) and lower (9.9%) for cyclic PRID-5 animals (by a factor of 0.4) compared with
the PRID-9 cyclic cows. These findings indicate that the proposed protocol achieves
similar results during the cool or warm season to those obtained when AI is conducted
at spontaneous estrus during the cool season. In addition, PRID-5 reduced twin
pregnancy compared with PRID-9.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.