Recent results of the searches for Supersymmetry in final states with one or two leptons at CMS are presented. Many Supersymmetry scenarios, including the Constrained Minimal Supersymmetric extension of the Standard Model (CMSSM), predict a substantial amount of events containing leptons, while the largest fraction of Standard Model background events -which are QCD interactions -gets strongly reduced by requiring isolated leptons. The analyzed data was taken in 2011 and corresponds to an integrated luminosity of approximately L = 1 fb −1 . The center-of-mass energy of the pp collisions was √ s = 7 TeV.

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Nowadays, medicinal herbs and their phytochemicals have emerged as a great therapeutic option for many disorders. However, poor bioavailability and selectivity might limit their clinical application. Therefore, bioavailability is considered a notable challenge to improve bio-efficacy in transporting dietary phytochemicals. Different methods have been proposed for generating effective carrier systems to enhance the bioavailability of phytochemicals. Among them, nano-vesicles have been introduced as promising candidates for the delivery of insoluble phytochemicals. Due to the easy preparation of the bilayer vesicles and their adaptability, they have been widely used and approved by the scientific literature. The first part of the review is focused on introducing phytosome technology as well as its applications, with emphasis on principles of formulations and characterization. The second part provides a wide overview of biological activities of commercial and non-commercial phytosomes, divided by systems and related pathologies. These results confirm the greater effectiveness of phytosomes, both in terms of biological activity or reduced dosage, highlighting curcumin and silymarin as the most formulated compounds. Finally, we describe the promising clinical and experimental findings regarding the applications of phytosomes. The conclusion of this study encourages the researchers to transfer their knowledge from laboratories to market, for a further development of these products.

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In a versatile modular scaffold system, gradient nonwovens of in situ crosslinked gelatin nanofibers (CGN), fabricated by reactive electrospinning, are laminated with perforated layers and nonwovens of thermoplastic non‐crosslinked biodegradable polyesters. The addition of glyoxal to a gelatin solution in a non‐toxic solvent mixture consisting of acetic acid, ethyl acetate, and water (5:3:2 w/w/w) enables the in situ crosslinking of gelatin nanofibers during electrospinning. The use of this fluorine‐free crosslinking system eliminates the need of post‐treatment crosslinking and purification steps typical for conventional CGN scaffolds. The slowly progressing crosslinking of the dissolved gelatin in the presence of glyoxal increases the viscosity of the gelatin solution during electrospinning so that the average diameter of the crosslinked gelatin nanofibers gradually increases from 90 to 680 nm. During the subsequent lamination process, alternating layers of CGN and polycaprolactone (PCL) nonwovens, produced by 3D microextrusion of micrometer‐sized PCL fibers, are bonded together upon heating above the PCL melting temperature. In contrast to the water‐soluble gelatin nanofibers and the comparatively weak CGN, the CGN/PCL/CGN layered biocomposites are water‐resistant and very robust. In such modular scaffold systems, strength, biodegradation rate, and biological functions can be controlled by varying the type, composition, fiber diameter, porosity, number, and sequence of the individual layers. The CGN/PCL multilayer biocomposites can be cut into any desired scaffold shape and attached to tissue by surgical sutures in order to suit the needs of individual patients.