This randomised clinical trail investigated the efficacy of a computerised cognitive remediation programme (NeurXercise TM ) in augmenting the presumed course of cognitive recovery following cessation of chronic alcohol abuse. Thirty-eight recently detoxified alcoholics were recruited from a residential substance abuse treatment programme and randomly divided into three groups; one group underwent 15 one-hour computerised remediation sessions, a second group underwent a time-matched audio-book placebo task, and a third group received no research intervention. Twenty-two participants completed the various treatment conditions as well as a battery of computerised and traditional neuropsychologica l tests designed for longitudina l measurement of changes in cognition. Results indicate that recently detoxified alcoholics experience improvement in cognition following detoxification. However, our findings did not support differential efficacy of a computerised cognitive remediation programme in augmenting this recovery process. These results are discussed in the light of methodological considerations which are relevant to cognitive remediation paradigms.
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